tetano
Editor, Senior Moderator
J Neonatal Perinatal Med
. 2022 Oct 26.
doi: 10.3233/NPM-220990. Online ahead of print.
Multisystem inflammatory syndrome in neonates associated with SARS-CoV-2 infection, a different entity?
L B Gámez-González[SUP] 1 [/SUP], A S Escrcega-Jurez[SUP] 2 [/SUP], D E Aguilar-Soto[SUP] 3 [/SUP], M Colmenero Rascón[SUP] 4 [/SUP], A C García Espinosa[SUP] 5 [/SUP], M A Yamazaki-Nakashimada[SUP] 6 [/SUP]
Affiliations
Abstract
Multisystemic inflammatory syndrome in children (MIS-C) is a novel disease that is associated with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV2). MIS-C usually affects children older than 5 years of age and adolescents, with a median of 8-years and an interquartile range of 3 to 11 years. A multisystemic inflammatory disease has been described in neonates and named MIS-N (multisystemic inflammatory syndrome in Neonates). We report three cases of Mexican newborns with MIS-N presenting with multiorgan compromise and a positive anti-SARS-CoV-2 IgG who developed Kawasaki disease (KD)-like cardiac features and discuss the current dilemma regarding diagnosis and treatment in these patients.
Keywords: COVID-19 neonate; SARS-CoV2; multisystem inflammatory syndrome in children.
. 2022 Oct 26.
doi: 10.3233/NPM-220990. Online ahead of print.
Multisystem inflammatory syndrome in neonates associated with SARS-CoV-2 infection, a different entity?
L B Gámez-González[SUP] 1 [/SUP], A S Escrcega-Jurez[SUP] 2 [/SUP], D E Aguilar-Soto[SUP] 3 [/SUP], M Colmenero Rascón[SUP] 4 [/SUP], A C García Espinosa[SUP] 5 [/SUP], M A Yamazaki-Nakashimada[SUP] 6 [/SUP]
Affiliations
- PMID: 36314218
- DOI: 10.3233/NPM-220990
Abstract
Multisystemic inflammatory syndrome in children (MIS-C) is a novel disease that is associated with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV2). MIS-C usually affects children older than 5 years of age and adolescents, with a median of 8-years and an interquartile range of 3 to 11 years. A multisystemic inflammatory disease has been described in neonates and named MIS-N (multisystemic inflammatory syndrome in Neonates). We report three cases of Mexican newborns with MIS-N presenting with multiorgan compromise and a positive anti-SARS-CoV-2 IgG who developed Kawasaki disease (KD)-like cardiac features and discuss the current dilemma regarding diagnosis and treatment in these patients.
Keywords: COVID-19 neonate; SARS-CoV2; multisystem inflammatory syndrome in children.