tetano
Editor, Senior Moderator
J Mol Med (Berl)
. 2020 Jun 13;1-8.
doi: 10.1007/s00109-020-01931-w. Online ahead of print.
COVID-19: Molecular Diagnostics Overview
Marlin Touma[SUP] 1 [/SUP]
Affiliations
Abstract
The last day of 2019 delivered the first report to the World Health Organization (WHO) about a group of cases of pneumonia of unknown etiology in Wuhan, China. Subsequent investigations identified the new comer, a novel coronavirus related to severe acute respiratory syndrome coronavirus (SARS-CoV) and thus was termed as SARS-CoV-2. Being very contagious, the new virus led the era of "COVID-19" which is the acronym of "coronavirus disease 2019," evoking an imminent threat to global health security with unprecedented devastating challenges to human kind. In this article, we provide a molecular overview on the SARS-CoV-2 virus and summarize tremendous efforts that have been made to develop a rapid confirmatory diagnostic test for COVID-19. The diagnostic performances of the available tests are analyzed based on the best current information from the early research.
Keywords: COVID-19; Coronavirus; SARS-CoV-2.
. 2020 Jun 13;1-8.
doi: 10.1007/s00109-020-01931-w. Online ahead of print.
COVID-19: Molecular Diagnostics Overview
Marlin Touma[SUP] 1 [/SUP]
Affiliations
- PMID: 32535768
- PMCID: PMC7293435
- DOI: 10.1007/s00109-020-01931-w
Abstract
The last day of 2019 delivered the first report to the World Health Organization (WHO) about a group of cases of pneumonia of unknown etiology in Wuhan, China. Subsequent investigations identified the new comer, a novel coronavirus related to severe acute respiratory syndrome coronavirus (SARS-CoV) and thus was termed as SARS-CoV-2. Being very contagious, the new virus led the era of "COVID-19" which is the acronym of "coronavirus disease 2019," evoking an imminent threat to global health security with unprecedented devastating challenges to human kind. In this article, we provide a molecular overview on the SARS-CoV-2 virus and summarize tremendous efforts that have been made to develop a rapid confirmatory diagnostic test for COVID-19. The diagnostic performances of the available tests are analyzed based on the best current information from the early research.
Keywords: COVID-19; Coronavirus; SARS-CoV-2.