tetano
Editor, Senior Moderator
J Microbiol Immunol Infect
. 2021 Mar 31;S1684-1182(21)00056-6.
doi: 10.1016/j.jmii.2021.03.004. Online ahead of print.
A novel SARS-CoV-2 IgG line-blot for evaluating discrepant IgG test results - Observations in pre-pandemic and follow-up samples of five patients
Andrea Steiner[SUP] 1 [/SUP], Mathias Pletz[SUP] 2 [/SUP], Bettina L?ffler[SUP] 3 [/SUP], Michael Baier[SUP] 4 [/SUP]
Affiliations
Abstract
To confirm discrepant SARS-CoV-2-IgG results in four standard assays we applied for the first time a prototype of a coronavirus IgG-line-blot which employs antigens from seasonal coronaviruses, SARS-1 and SARS-CoV-2 combined with avidity testing as a confirmatory tool in a follow-up of five cases including pre-pandemic samples.
Keywords: COVID-19; Line blot; Nucleocapsid; SARS-CoV-2; Serology; Specific antibodies; Spike protein.
. 2021 Mar 31;S1684-1182(21)00056-6.
doi: 10.1016/j.jmii.2021.03.004. Online ahead of print.
A novel SARS-CoV-2 IgG line-blot for evaluating discrepant IgG test results - Observations in pre-pandemic and follow-up samples of five patients
Andrea Steiner[SUP] 1 [/SUP], Mathias Pletz[SUP] 2 [/SUP], Bettina L?ffler[SUP] 3 [/SUP], Michael Baier[SUP] 4 [/SUP]
Affiliations
- PMID: 33849809
- DOI: 10.1016/j.jmii.2021.03.004
Abstract
To confirm discrepant SARS-CoV-2-IgG results in four standard assays we applied for the first time a prototype of a coronavirus IgG-line-blot which employs antigens from seasonal coronaviruses, SARS-1 and SARS-CoV-2 combined with avidity testing as a confirmatory tool in a follow-up of five cases including pre-pandemic samples.
Keywords: COVID-19; Line blot; Nucleocapsid; SARS-CoV-2; Serology; Specific antibodies; Spike protein.