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J Med Virol . What are the long-term holistic health consequences of COVID-19 among survivors? An umbrella systematic review

tetano

Editor, Senior Moderator
J Med Virol


. 2022 Aug 24.
doi: 10.1002/jmv.28086. Online ahead of print.
What are the long-term holistic health consequences of COVID-19 among survivors? An umbrella systematic review


Catherine Paterson[SUP] 1 2 3 4 5 [/SUP], Deborah Davis[SUP] 1 3 4 [/SUP], Michael Roche[SUP] 1 3 4 6 [/SUP], Bernie Bissett[SUP] 1 [/SUP], Cara Roberts[SUP] 1 2 3 [/SUP], Murray Turner[SUP] 1 [/SUP], Emma Baldock[SUP] 7 [/SUP], Imogen Mitchell[SUP] 8 9 [/SUP]



Affiliations

Abstract

Introduction: Many people who have survived COVID-19 have experienced negative persistent impacts on health. Impacts on health have included persistent respiratory symptoms, decreased quality of life, fatigue, impaired functional capacity, memory deficits, psychological impacts, and difficulties in returning to paid employment. Evidence is yet to be pooled to inform future directions in research and practice.
Aim: To determine the physical, psychological, social, and spiritual impacts of the illness which extend beyond the acute phase of COVID-19 survivors.
Method: This umbrella review (review of systematic reviews) critically synthesised physical (including abnormal laboratory parameters), psychological, social, and spiritual impacts which extended beyond the acute phase of COVID-19 survivors. The search strategy was based on the SPIDER model and all publications were double screened independently by four review authors for the eligibility criteria. Data extraction and quality assessment were conducted in parallel independently.
Results: 18 systematic reviews were included, which represented a total of 493 publications. Sample sizes ranged from n=15 to n=44,799 with a total of n=295,455 participants. There was incomplete reporting of several significant data points including the description of the SARS CoV2 variant, COVID-19 treatments, and key clinical and demographic data. A number of physical, psychological, social impacts were identified for individuals grappling with Post-COVID condition.
Conclusion: The long term sequalae of acute COVID-19 and size of the problem is only beginning to emerge. Further investigation is needed to ensure those affected by Post-COVID condition have their informational, spiritual, psychological, social, and physical needs met in the future. This article is protected by copyright. All rights reserved.

Keywords: Coronavirus; Epidemiology; Pandemics; SARS coronavirus; Virus classification; Virus classificationVirus classificationVirus classification.
 
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