tetano
Editor, Senior Moderator
J Med Virol
. 2020 Nov 17.
doi: 10.1002/jmv.26667. Online ahead of print.
The other side of COVID-19 pandemic: Effects on male fertility
Cemile Merve Seymen[SUP] 1 [/SUP]
Affiliations
Abstract
The outbreak of novel Coronavirus Disease 2019 (COVID-19) has become a major pandemic threat worldwide. According to the existing clinical data, this virus not only causes respiratory diseases and affects the lungs but also induces the histopathological or functional changes in various organs like the testis and also the male genital tract. The Renin-Angiotensin System (RAS), also ACE 2 and TMPRSS2 play an important role in a cellular entry for SARS-CoV-2. Because of the male genital system presents high ACE 2 expression, the importance of this pathway increases in COVID-19 cases. Due to the COVID-19 pandemic affects the male genital system in direct or indirect ways and shows a negative impact on male reproduction, this paper focuses on the possible mechanisms underlying the damage caused by COVID-19 to the testis and also other components of the male genital tract. This article is protected by copyright. All rights reserved.
Keywords: coronavirus; genital tract; pandemics.
. 2020 Nov 17.
doi: 10.1002/jmv.26667. Online ahead of print.
The other side of COVID-19 pandemic: Effects on male fertility
Cemile Merve Seymen[SUP] 1 [/SUP]
Affiliations
- PMID: 33200417
- DOI: 10.1002/jmv.26667
Abstract
The outbreak of novel Coronavirus Disease 2019 (COVID-19) has become a major pandemic threat worldwide. According to the existing clinical data, this virus not only causes respiratory diseases and affects the lungs but also induces the histopathological or functional changes in various organs like the testis and also the male genital tract. The Renin-Angiotensin System (RAS), also ACE 2 and TMPRSS2 play an important role in a cellular entry for SARS-CoV-2. Because of the male genital system presents high ACE 2 expression, the importance of this pathway increases in COVID-19 cases. Due to the COVID-19 pandemic affects the male genital system in direct or indirect ways and shows a negative impact on male reproduction, this paper focuses on the possible mechanisms underlying the damage caused by COVID-19 to the testis and also other components of the male genital tract. This article is protected by copyright. All rights reserved.
Keywords: coronavirus; genital tract; pandemics.