tetano
Editor, Senior Moderator
J Med Virol
. 2021 Apr 30.
doi: 10.1002/jmv.27055. Online ahead of print.
The breadth of concomitant virological features in a family cluster outbreak of COVID-19 pneumonia
Guanglin Lei[SUP] 1 [/SUP], Fanping Meng[SUP] 1 [/SUP], Cheng Wang[SUP] 2 [/SUP], Jin Yan[SUP] 1 [/SUP], Fang Sun[SUP] 1 [/SUP], Lei Shi[SUP] 1 [/SUP], Wengang Li[SUP] 1 [/SUP], Junqing Luan[SUP] 1 [/SUP], Shiyu Wang[SUP] 1 [/SUP], Penghui Yang[SUP] 1 [/SUP]
Affiliations
Abstract
An outbreak of a novel coronavirus disease (COVID-19) caused by SARS-CoV-2 had emerged in 2019 and rapidly posed a global epidemic. Here, we report the breadth of concomitant virological features of a family cluster with COVID-19. The period of virus shedding is significantly different between upper respiratory and feces samples. Even the SARS-CoV-2 virus titers were undetectable in feces, it could be positive again soon and likely related to fluctuated inflammation levels (IL-6, etc.) and lowered immune responses (CD4+ T lymphocyte, etc.). Our findings expand the novel understanding of the breadth of concomitant virological features during a non-severe family cluster of COVID-19. This article is protected by copyright. All rights reserved.
. 2021 Apr 30.
doi: 10.1002/jmv.27055. Online ahead of print.
The breadth of concomitant virological features in a family cluster outbreak of COVID-19 pneumonia
Guanglin Lei[SUP] 1 [/SUP], Fanping Meng[SUP] 1 [/SUP], Cheng Wang[SUP] 2 [/SUP], Jin Yan[SUP] 1 [/SUP], Fang Sun[SUP] 1 [/SUP], Lei Shi[SUP] 1 [/SUP], Wengang Li[SUP] 1 [/SUP], Junqing Luan[SUP] 1 [/SUP], Shiyu Wang[SUP] 1 [/SUP], Penghui Yang[SUP] 1 [/SUP]
Affiliations
- PMID: 33930189
- DOI: 10.1002/jmv.27055
Abstract
An outbreak of a novel coronavirus disease (COVID-19) caused by SARS-CoV-2 had emerged in 2019 and rapidly posed a global epidemic. Here, we report the breadth of concomitant virological features of a family cluster with COVID-19. The period of virus shedding is significantly different between upper respiratory and feces samples. Even the SARS-CoV-2 virus titers were undetectable in feces, it could be positive again soon and likely related to fluctuated inflammation levels (IL-6, etc.) and lowered immune responses (CD4+ T lymphocyte, etc.). Our findings expand the novel understanding of the breadth of concomitant virological features during a non-severe family cluster of COVID-19. This article is protected by copyright. All rights reserved.