tetano
Editor, Senior Moderator
J Med Virol
. 2024 Aug;96(8):e29847.
doi: 10.1002/jmv.29847. Temporal patterns of asymptomatic SARS-CoV-2 infection among pediatric population in Japan: A 3-year analysis
Kei Kozawa[SUP] 1 [/SUP], Yuki Higashimoto[SUP] 2 [/SUP], Yoshiki Kawamura[SUP] 1 [/SUP], Hiroki Miura[SUP] 1 [/SUP], Fumihiko Hattori[SUP] 3 [/SUP], Yuka Mihara[SUP] 4 [/SUP], Hidetaka Nakai[SUP] 3 [/SUP], Naoko Nishimura[SUP] 5 [/SUP], Takao Ozaki[SUP] 5 [/SUP], Masaru Ihira[SUP] 6 [/SUP], Tetsushi Yoshikawa[SUP] 1 [/SUP]
Affiliations
To elucidate the seroprevalence and rate of asymptomatic infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Japanese children, serological analysis was performed using serum samples collected from March 2020 to February 2023. A total of 1493 serum samples were collected during the first study period (March 2020 to February 2021). None of the serum samples was positive for SARS-CoV-2 antibody. In the second period (March 2021 to February 2022), seven of the 1055 patients (0.7%) experienced SARS-CoV-2 infection. The third period (March 2022 to February 2023) was divided into three terms: from March to June 30, 2022; from July to October 2022; and from November 2022 to February 2023. The seroprevalence gradually increased throughout this period, with rates of 6.0%, 18.6%, and 30.4% in the three terms, respectively. Pediatric cases of asymptomatic SARS-CoV-2 infection occurred after the surge of Omicron variants. Since none of the SARS-CoV-2 antibody-positive patients had a previous history of coronavirus disease 2019, the seroprevalence rate in this study may represent the rate of asymptomatic infection.
Keywords: COVID‐19; SARS‐CoV‐2; asymptomatic infection; seroprevalence.
. 2024 Aug;96(8):e29847.
doi: 10.1002/jmv.29847. Temporal patterns of asymptomatic SARS-CoV-2 infection among pediatric population in Japan: A 3-year analysis
Kei Kozawa[SUP] 1 [/SUP], Yuki Higashimoto[SUP] 2 [/SUP], Yoshiki Kawamura[SUP] 1 [/SUP], Hiroki Miura[SUP] 1 [/SUP], Fumihiko Hattori[SUP] 3 [/SUP], Yuka Mihara[SUP] 4 [/SUP], Hidetaka Nakai[SUP] 3 [/SUP], Naoko Nishimura[SUP] 5 [/SUP], Takao Ozaki[SUP] 5 [/SUP], Masaru Ihira[SUP] 6 [/SUP], Tetsushi Yoshikawa[SUP] 1 [/SUP]
Affiliations
- PMID: 39105394
- DOI: 10.1002/jmv.29847
To elucidate the seroprevalence and rate of asymptomatic infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Japanese children, serological analysis was performed using serum samples collected from March 2020 to February 2023. A total of 1493 serum samples were collected during the first study period (March 2020 to February 2021). None of the serum samples was positive for SARS-CoV-2 antibody. In the second period (March 2021 to February 2022), seven of the 1055 patients (0.7%) experienced SARS-CoV-2 infection. The third period (March 2022 to February 2023) was divided into three terms: from March to June 30, 2022; from July to October 2022; and from November 2022 to February 2023. The seroprevalence gradually increased throughout this period, with rates of 6.0%, 18.6%, and 30.4% in the three terms, respectively. Pediatric cases of asymptomatic SARS-CoV-2 infection occurred after the surge of Omicron variants. Since none of the SARS-CoV-2 antibody-positive patients had a previous history of coronavirus disease 2019, the seroprevalence rate in this study may represent the rate of asymptomatic infection.
Keywords: COVID‐19; SARS‐CoV‐2; asymptomatic infection; seroprevalence.