tetano
Editor, Senior Moderator
J Med Virol. 2020 Apr 20. doi: 10.1002/jmv.25904. [Epub ahead of print]
Serological tests facilitate identification of asymptomatic SARS-CoV-2 infection in Wuhan, China.
Wu X[SUP]1[/SUP], Fu B[SUP]2[/SUP], Chen L[SUP]3[/SUP], Feng Y[SUP]4[/SUP].
Author information
Abstract
The Wuhan City has ended the lockdown and people have been allowed to resume working since April 8 if meeting a set of COVID-19-associated tests including SARS-CoV-2 nucleic acid test (NAT) of nasopharyngeal swabs, chest CT scan or a SARS-CoV-2-specific serological test. Here, we reported the positive rate of COVID-19 tests based on NAT, chest CT scan and a serological SARS-CoV-2 test, from April 3 to 15 in one hospital in Qingshan Destrict, Wuhan. We observed a ~10% SARS-CoV-2-specific IgG positive rate from 1,402 tests. Combination of SARS-CoV-2 NAT and a specific serological test might facilitate the detection of COVID-19 infection, or the asymptomatic SARS-CoV-2-infected subjects. Large-scale investigation is required to evaluate the herd immunity of the city, for the resuming people and for the re-opened city. This article is protected by copyright. All rights reserved.
This article is protected by copyright. All rights reserved.
KEYWORDS:
Coronavirus < Virus classification; Humoral immunity < Immune responses; Inapparent infection < Epidemiology
PMID:32311142DOI:10.1002/jmv.25904
Serological tests facilitate identification of asymptomatic SARS-CoV-2 infection in Wuhan, China.
Wu X[SUP]1[/SUP], Fu B[SUP]2[/SUP], Chen L[SUP]3[/SUP], Feng Y[SUP]4[/SUP].
Author information
Abstract
The Wuhan City has ended the lockdown and people have been allowed to resume working since April 8 if meeting a set of COVID-19-associated tests including SARS-CoV-2 nucleic acid test (NAT) of nasopharyngeal swabs, chest CT scan or a SARS-CoV-2-specific serological test. Here, we reported the positive rate of COVID-19 tests based on NAT, chest CT scan and a serological SARS-CoV-2 test, from April 3 to 15 in one hospital in Qingshan Destrict, Wuhan. We observed a ~10% SARS-CoV-2-specific IgG positive rate from 1,402 tests. Combination of SARS-CoV-2 NAT and a specific serological test might facilitate the detection of COVID-19 infection, or the asymptomatic SARS-CoV-2-infected subjects. Large-scale investigation is required to evaluate the herd immunity of the city, for the resuming people and for the re-opened city. This article is protected by copyright. All rights reserved.
This article is protected by copyright. All rights reserved.
KEYWORDS:
Coronavirus < Virus classification; Humoral immunity < Immune responses; Inapparent infection < Epidemiology
PMID:32311142DOI:10.1002/jmv.25904