tetano
Editor, Senior Moderator
J Med Virol
. 2021 Jun 29.
doi: 10.1002/jmv.27167. Online ahead of print.
Phylogenomics reveals multiple introductions and early spread of SARS-CoV-2 into Peru
Eduardo Juscamayta-López[SUP] 1 2 [/SUP], Dennis Carhuaricra[SUP] 2 [/SUP], David Tarazona[SUP] 1 2 [/SUP], Faviola Valdivia[SUP] 1 [/SUP], Nancy Rojas[SUP] 1 [/SUP], Lenin Maturrano[SUP] 2 [/SUP], Ronnie Gavilán[SUP] 1 [/SUP]
Affiliations
Abstract
Peru has become one of the countries with the highest mortality rates from the current coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). To investigate early transmission events and the genomic diversity of SARS-CoV-2 isolates circulating in Peru in the early COVID-19 pandemic, we analyzed 3472 viral genomes, of which 149 were from Peru. Phylogenomic analysis revealed multiple and independent introductions of the virus likely from Europe and Asia, and high diversity of genetic lineages circulating in Peru. In addition, we found evidence for community-driven transmission of SARS-CoV-2 as suggested by clusters of related viruses found in patients living in different regions of Peru. This article is protected by copyright. All rights reserved.
Keywords: SARS-CoV-2; evolution; molecular epidemiology; phylogenomics; transmission; whole-genome sequencing.
. 2021 Jun 29.
doi: 10.1002/jmv.27167. Online ahead of print.
Phylogenomics reveals multiple introductions and early spread of SARS-CoV-2 into Peru
Eduardo Juscamayta-López[SUP] 1 2 [/SUP], Dennis Carhuaricra[SUP] 2 [/SUP], David Tarazona[SUP] 1 2 [/SUP], Faviola Valdivia[SUP] 1 [/SUP], Nancy Rojas[SUP] 1 [/SUP], Lenin Maturrano[SUP] 2 [/SUP], Ronnie Gavilán[SUP] 1 [/SUP]
Affiliations
- PMID: 34185310
- DOI: 10.1002/jmv.27167
Abstract
Peru has become one of the countries with the highest mortality rates from the current coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). To investigate early transmission events and the genomic diversity of SARS-CoV-2 isolates circulating in Peru in the early COVID-19 pandemic, we analyzed 3472 viral genomes, of which 149 were from Peru. Phylogenomic analysis revealed multiple and independent introductions of the virus likely from Europe and Asia, and high diversity of genetic lineages circulating in Peru. In addition, we found evidence for community-driven transmission of SARS-CoV-2 as suggested by clusters of related viruses found in patients living in different regions of Peru. This article is protected by copyright. All rights reserved.
Keywords: SARS-CoV-2; evolution; molecular epidemiology; phylogenomics; transmission; whole-genome sequencing.