tetano
Editor, Senior Moderator
J Med Virol
. 2022 Nov 15.
doi: 10.1002/jmv.28311. Online ahead of print.
Pathogenesis and histological changes of nephropathy associated with COVID-19
Lirong Lin[SUP] 1 [/SUP], Junhui Deng[SUP] 1 [/SUP], Jie Li[SUP] 2 [/SUP], Luquan Zheng[SUP] 1 [/SUP], Zhifeng Wu[SUP] 1 [/SUP], Wei Tan[SUP] 1 [/SUP], Jurong Yang[SUP] 1 [/SUP]
Affiliations
Abstract
Coronavirus disease 2019 (COVID-19) can cause damage to multiple organ, not only to the lungs, but also to the kidneys. Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) can cause acute and chronic kidney disease through direct viral infection, indirect injury, and vaccination-related injury. Like lung injury, kidney injury is also an important aspect affecting the severity and prognosis of SARS-CoV-2. This article summarizes the pathogenesis, pathological manifestations, and clinical features of SARS-CoV-2 direct or indirect renal injury. Including direct injury, indirect injury, special comorbidities (receiving kidney transplantation and CKD), and vaccine-related renal injury, and exploring the possible therapeutic effect of anti-SARS-CoV-2 therapy on renal injury. The purpose is to provide reference for understanding COVID-19-related renal injury, guiding clinical and pathological diagnosis and treatment, and evaluating prognosis. This article is protected by copyright. All rights reserved.
Keywords: COVID-19; SARS-CoV-2; histological; kidney injury.
. 2022 Nov 15.
doi: 10.1002/jmv.28311. Online ahead of print.
Pathogenesis and histological changes of nephropathy associated with COVID-19
Lirong Lin[SUP] 1 [/SUP], Junhui Deng[SUP] 1 [/SUP], Jie Li[SUP] 2 [/SUP], Luquan Zheng[SUP] 1 [/SUP], Zhifeng Wu[SUP] 1 [/SUP], Wei Tan[SUP] 1 [/SUP], Jurong Yang[SUP] 1 [/SUP]
Affiliations
- PMID: 36377540
- DOI: 10.1002/jmv.28311
Abstract
Coronavirus disease 2019 (COVID-19) can cause damage to multiple organ, not only to the lungs, but also to the kidneys. Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) can cause acute and chronic kidney disease through direct viral infection, indirect injury, and vaccination-related injury. Like lung injury, kidney injury is also an important aspect affecting the severity and prognosis of SARS-CoV-2. This article summarizes the pathogenesis, pathological manifestations, and clinical features of SARS-CoV-2 direct or indirect renal injury. Including direct injury, indirect injury, special comorbidities (receiving kidney transplantation and CKD), and vaccine-related renal injury, and exploring the possible therapeutic effect of anti-SARS-CoV-2 therapy on renal injury. The purpose is to provide reference for understanding COVID-19-related renal injury, guiding clinical and pathological diagnosis and treatment, and evaluating prognosis. This article is protected by copyright. All rights reserved.
Keywords: COVID-19; SARS-CoV-2; histological; kidney injury.