tetano
Editor, Senior Moderator
J Med Virol
. 2021 Mar 23.
doi: 10.1002/jmv.26956. Online ahead of print.
Outcomes among 10,314 hospitalized COVID-19 patients at a tertiary care government hospital in Delhi, India
Vikas Malhotra[SUP] 1 [/SUP], Saurav Basu[SUP] 2 [/SUP], Nandini Sharma[SUP] 2 [/SUP], Suresh Kumar[SUP] 3 [/SUP], Sandeep Garg[SUP] 4 [/SUP], Kumar Dushyant[SUP] 2 [/SUP], Amod Borle[SUP] 2 [/SUP]
Affiliations
Abstract
A significant proportion of COVID-19 disease patients require timely hospitalization to reduce the risk of complications and mortality. We describe the trends of the age and gender stratified outcomes among hospitalized COVID-19 patients with moderate to severe illness, at the largest dedicated tertiary care COVID-19 government hospital in New Delhi, India. A retrospective cohort study through secondary data analysis from in-patient hospital data of patients admitted from April 1-November 15' 2020 was conducted. The data of 10,314 laboratory-confirmed COVID-19 patients was analyzed, of which 8,899 (86.28%) were discharged after recovery, and 1,415 (13.72%) died. The mean (SD) age of the hospitalized patients was 46.43 (18.74) years (n=10,309) including 6,031 (58.50%) male and 4,278 (41.50%) female patients (n=10,309). On bivariate analysis, increasing age was associated with significantly higher odds of mortality in both gender (p<0.001). The mortality rate in female patients was lower (11.92%) compared to male patients (15.75%) (p=0.675). However, elderly women had the highest odds of mortality (p<0.001), indicating the possible role of delayed health seeking behavior, secondary to familial and social neglect. Mortality in the COVID-19 patients also occurred early after admission suggesting rapid deterioration, delayed reporting by patients, or their late referral from other health facilities. However, the overall statewide recovery rate showed steady improvement since the onset of the pandemic. In contrast, the recovery rate among the moderate-severe cases that were hospitalized at this tertiary care centre during the same period reflected a lower non-specific zigzag pattern indicating limited effectiveness of the COVID-19 treatment regimens. This article is protected by copyright. All rights reserved.
Keywords: COVID-19; Coronavirus; Epidemiology; Pandemic; Recovery rate.
. 2021 Mar 23.
doi: 10.1002/jmv.26956. Online ahead of print.
Outcomes among 10,314 hospitalized COVID-19 patients at a tertiary care government hospital in Delhi, India
Vikas Malhotra[SUP] 1 [/SUP], Saurav Basu[SUP] 2 [/SUP], Nandini Sharma[SUP] 2 [/SUP], Suresh Kumar[SUP] 3 [/SUP], Sandeep Garg[SUP] 4 [/SUP], Kumar Dushyant[SUP] 2 [/SUP], Amod Borle[SUP] 2 [/SUP]
Affiliations
- PMID: 33755238
- DOI: 10.1002/jmv.26956
Abstract
A significant proportion of COVID-19 disease patients require timely hospitalization to reduce the risk of complications and mortality. We describe the trends of the age and gender stratified outcomes among hospitalized COVID-19 patients with moderate to severe illness, at the largest dedicated tertiary care COVID-19 government hospital in New Delhi, India. A retrospective cohort study through secondary data analysis from in-patient hospital data of patients admitted from April 1-November 15' 2020 was conducted. The data of 10,314 laboratory-confirmed COVID-19 patients was analyzed, of which 8,899 (86.28%) were discharged after recovery, and 1,415 (13.72%) died. The mean (SD) age of the hospitalized patients was 46.43 (18.74) years (n=10,309) including 6,031 (58.50%) male and 4,278 (41.50%) female patients (n=10,309). On bivariate analysis, increasing age was associated with significantly higher odds of mortality in both gender (p<0.001). The mortality rate in female patients was lower (11.92%) compared to male patients (15.75%) (p=0.675). However, elderly women had the highest odds of mortality (p<0.001), indicating the possible role of delayed health seeking behavior, secondary to familial and social neglect. Mortality in the COVID-19 patients also occurred early after admission suggesting rapid deterioration, delayed reporting by patients, or their late referral from other health facilities. However, the overall statewide recovery rate showed steady improvement since the onset of the pandemic. In contrast, the recovery rate among the moderate-severe cases that were hospitalized at this tertiary care centre during the same period reflected a lower non-specific zigzag pattern indicating limited effectiveness of the COVID-19 treatment regimens. This article is protected by copyright. All rights reserved.
Keywords: COVID-19; Coronavirus; Epidemiology; Pandemic; Recovery rate.