tetano
Editor, Senior Moderator
J Med Virol
. 2024 Jul;96(7):e29773.
doi: 10.1002/jmv.29773. Dispersal history of SARS-CoV-2 in Galicia, Spain
Pilar Gallego-García[SUP] 1 2 [/SUP], Nuria Estévez-Gómez[SUP] 1 2 [/SUP], Loretta De Chiara[SUP] 1 2 3 [/SUP], Pilar Alvariño[SUP] 1 [/SUP], Pedro M Juiz-González[SUP] 4 [/SUP], Isabel Torres-Beceiro[SUP] 4 [/SUP], Margarita Poza[SUP] 5 6 [/SUP], Juan A Vallejo[SUP] 5 [/SUP], Soraya Rumbo-Feal[SUP] 5 [/SUP], Kelly Conde-Pérez[SUP] 5 [/SUP], Pablo Aja-Macaya[SUP] 5 [/SUP], Susana Ladra[SUP] 7 [/SUP], Antonio Moreno-Flores[SUP] 8 [/SUP], María J Gude-González[SUP] 8 [/SUP], Amparo Coira[SUP] 9 [/SUP], Antonio Aguilera[SUP] 9 [/SUP], José J Costa-Alcalde[SUP] 9 [/SUP], Rocío Trastoy[SUP] 9 [/SUP], Gema Barbeito-Castiñeiras[SUP] 9 [/SUP], Daniel García-Souto[SUP] 10 [/SUP], José M C Tubio[SUP] 10 11 [/SUP], Matilde Trigo-Daporta[SUP] 12 [/SUP], Pablo Camacho-Zamora[SUP] 12 [/SUP], Juan García Costa[SUP] 13 [/SUP], María González-Domínguez[SUP] 13 [/SUP], Luis Canoura-Fernández[SUP] 13 [/SUP], Daniel Glez-Peña[SUP] 1 2 [/SUP], Sonia Pérez-Castro[SUP] 14 15 [/SUP], Jorge J Cabrera[SUP] 14 15 [/SUP], Carlos Daviña-Núñez[SUP] 15 [/SUP], Montserrat Godoy-Diz[SUP] 14 [/SUP], Ana Belén Treinta-Álvarez[SUP] 14 [/SUP], Maria Isabel Veiga[SUP] 16 17 [/SUP], João Carlos Sousa[SUP] 16 17 [/SUP], Nuno S Osório[SUP] 16 17 [/SUP], Iñaki Comas[SUP] 18 19 20 [/SUP], Fernando González-Candelas[SUP] 19 20 21 [/SUP], Samuel L Hong[SUP] 22 [/SUP], Nena Bollen[SUP] 22 [/SUP], Simon Dellicour[SUP] 22 23 [/SUP], Guy Baele[SUP] 22 [/SUP], Marc A Suchard[SUP] 24 25 26 [/SUP], Philippe Lemey[SUP] 22 27 [/SUP], Andrés Agulla[SUP] 4 [/SUP], Germán Bou[SUP] 5 [/SUP], Pilar Alonso-García[SUP] 8 [/SUP], María Luisa Pérez-Del-Molino[SUP] 9 [/SUP], Marta García-Campello[SUP] 12 [/SUP], Isabel Paz-Vidal[SUP] 13 [/SUP], Benito Regueiro[SUP] 14 15 [/SUP], David Posada[SUP] 1 2 3 [/SUP]
Affiliations
The dynamics of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission are influenced by a variety of factors, including social restrictions and the emergence of distinct variants. In this study, we delve into the origins and dissemination of the Alpha, Delta, and Omicron-BA.1 variants of concern in Galicia, northwest Spain. For this, we leveraged genomic data collected by the EPICOVIGAL Consortium and from the GISAID database, along with mobility information from other Spanish regions and foreign countries. Our analysis indicates that initial introductions during the Alpha phase were predominantly from other Spanish regions and France. However, as the pandemic progressed, introductions from Portugal and the United States became increasingly significant. The number of detected introductions varied from 96 and 101 for Alpha and Delta to 39 for Omicron-BA.1. Most of these introductions left a low number of descendants (<10), suggesting a limited impact on the evolution of the pandemic in Galicia. Notably, Galicia's major coastal cities emerged as critical hubs for viral transmission, highlighting their role in sustaining and spreading the virus. This research emphasizes the critical role of regional connectivity in the spread of SARS-CoV-2 and offers essential insights for enhancing public health strategies and surveillance measures.
Keywords: SARS‐CoV‐2; dispersal; phylogeography; variants of concern.
. 2024 Jul;96(7):e29773.
doi: 10.1002/jmv.29773. Dispersal history of SARS-CoV-2 in Galicia, Spain
Pilar Gallego-García[SUP] 1 2 [/SUP], Nuria Estévez-Gómez[SUP] 1 2 [/SUP], Loretta De Chiara[SUP] 1 2 3 [/SUP], Pilar Alvariño[SUP] 1 [/SUP], Pedro M Juiz-González[SUP] 4 [/SUP], Isabel Torres-Beceiro[SUP] 4 [/SUP], Margarita Poza[SUP] 5 6 [/SUP], Juan A Vallejo[SUP] 5 [/SUP], Soraya Rumbo-Feal[SUP] 5 [/SUP], Kelly Conde-Pérez[SUP] 5 [/SUP], Pablo Aja-Macaya[SUP] 5 [/SUP], Susana Ladra[SUP] 7 [/SUP], Antonio Moreno-Flores[SUP] 8 [/SUP], María J Gude-González[SUP] 8 [/SUP], Amparo Coira[SUP] 9 [/SUP], Antonio Aguilera[SUP] 9 [/SUP], José J Costa-Alcalde[SUP] 9 [/SUP], Rocío Trastoy[SUP] 9 [/SUP], Gema Barbeito-Castiñeiras[SUP] 9 [/SUP], Daniel García-Souto[SUP] 10 [/SUP], José M C Tubio[SUP] 10 11 [/SUP], Matilde Trigo-Daporta[SUP] 12 [/SUP], Pablo Camacho-Zamora[SUP] 12 [/SUP], Juan García Costa[SUP] 13 [/SUP], María González-Domínguez[SUP] 13 [/SUP], Luis Canoura-Fernández[SUP] 13 [/SUP], Daniel Glez-Peña[SUP] 1 2 [/SUP], Sonia Pérez-Castro[SUP] 14 15 [/SUP], Jorge J Cabrera[SUP] 14 15 [/SUP], Carlos Daviña-Núñez[SUP] 15 [/SUP], Montserrat Godoy-Diz[SUP] 14 [/SUP], Ana Belén Treinta-Álvarez[SUP] 14 [/SUP], Maria Isabel Veiga[SUP] 16 17 [/SUP], João Carlos Sousa[SUP] 16 17 [/SUP], Nuno S Osório[SUP] 16 17 [/SUP], Iñaki Comas[SUP] 18 19 20 [/SUP], Fernando González-Candelas[SUP] 19 20 21 [/SUP], Samuel L Hong[SUP] 22 [/SUP], Nena Bollen[SUP] 22 [/SUP], Simon Dellicour[SUP] 22 23 [/SUP], Guy Baele[SUP] 22 [/SUP], Marc A Suchard[SUP] 24 25 26 [/SUP], Philippe Lemey[SUP] 22 27 [/SUP], Andrés Agulla[SUP] 4 [/SUP], Germán Bou[SUP] 5 [/SUP], Pilar Alonso-García[SUP] 8 [/SUP], María Luisa Pérez-Del-Molino[SUP] 9 [/SUP], Marta García-Campello[SUP] 12 [/SUP], Isabel Paz-Vidal[SUP] 13 [/SUP], Benito Regueiro[SUP] 14 15 [/SUP], David Posada[SUP] 1 2 3 [/SUP]
Affiliations
- PMID: 38940448
- DOI: 10.1002/jmv.29773
The dynamics of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission are influenced by a variety of factors, including social restrictions and the emergence of distinct variants. In this study, we delve into the origins and dissemination of the Alpha, Delta, and Omicron-BA.1 variants of concern in Galicia, northwest Spain. For this, we leveraged genomic data collected by the EPICOVIGAL Consortium and from the GISAID database, along with mobility information from other Spanish regions and foreign countries. Our analysis indicates that initial introductions during the Alpha phase were predominantly from other Spanish regions and France. However, as the pandemic progressed, introductions from Portugal and the United States became increasingly significant. The number of detected introductions varied from 96 and 101 for Alpha and Delta to 39 for Omicron-BA.1. Most of these introductions left a low number of descendants (<10), suggesting a limited impact on the evolution of the pandemic in Galicia. Notably, Galicia's major coastal cities emerged as critical hubs for viral transmission, highlighting their role in sustaining and spreading the virus. This research emphasizes the critical role of regional connectivity in the spread of SARS-CoV-2 and offers essential insights for enhancing public health strategies and surveillance measures.
Keywords: SARS‐CoV‐2; dispersal; phylogeography; variants of concern.