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J Med Virol . Clinical Presentations of Adult and Pediatric SARS-CoV-2-Positive Cases in a Community Cohort, Nashville, Tennessee

tetano

Editor, Senior Moderator
J Med Virol


. 2022 Jul 11.
doi: 10.1002/jmv.27988. Online ahead of print.
Clinical Presentations of Adult and Pediatric SARS-CoV-2-Positive Cases in a Community Cohort, Nashville, Tennessee


Danielle A Rankin[SUP] 1 2 [/SUP], Ahmad Yanis[SUP] 1 [/SUP], Rana Talj[SUP] 1 [/SUP], Harrison L Howe[SUP] 1 [/SUP], Sean M Bloos[SUP] 1 3 [/SUP], Kailee N Fernandez[SUP] 1 [/SUP], Justin Z Amarin[SUP] 1 [/SUP], Mercedes Bruce[SUP] 1 [/SUP], Seifein Salib[SUP] 1 [/SUP], Samarian Hargrave[SUP] 1 [/SUP], James D Chappell[SUP] 1 [/SUP], Andrew J Spieker[SUP] 4 [/SUP], Natasha B Halasa[SUP] 1 [/SUP], Leigh M Howard[SUP] 1 [/SUP]



Affiliations

Abstract

Compared to adults, the prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) illness in children has been lower and less severe. However, reports comparing SARS-CoV-2 infection among children and adults are limited. As part of our longitudinal cohort study of adults and children with SARS-CoV-2 infection and their household contacts in Nashville, Tennessee, we compared the clinical characteristics and outcomes of SARS-CoV-2 infections between children and adults. Children were more likely to be asymptomatically infected and had a shorter illness duration compared to adults. The differences observed in clinical presentation across ages may inform symptom-specific testing, screening, and management algorithms. This article is protected by copyright. All rights reserved.

Keywords: COVID-19 in adults; Pediatric COVID-19; SARS-CoV-2-positive adults; SARS-CoV-2-positive children.
 
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