tetano
Editor, Senior Moderator
J Med Virol
. 2020 Aug 11.
doi: 10.1002/jmv.26414. Online ahead of print.
Clinical Characteristics of Moderate COVID-19 Patients Aggravation in Wuhan Stadium Cabin Hospital: A 571 Cases of Retrospective Cohort Study
Lei Shu[SUP] 1 2 [/SUP], Xiaoyan Wang[SUP] 3 [/SUP], Mingquan Li[SUP] 4 [/SUP], Xiaolin Chen[SUP] 1 [/SUP], Ningfei Ji[SUP] 5 [/SUP], Lei Shi[SUP] 1 [/SUP], Mingjing Wu[SUP] 1 [/SUP], Kaili Deng[SUP] 1 [/SUP], Jing Wei[SUP] 1 [/SUP], Xueli Wang[SUP] 1 [/SUP], Yang Cao[SUP] 1 [/SUP], Jiaxin Yan[SUP] 1 [/SUP], Ganzhu Feng[SUP] 6 [/SUP]
Affiliations
Abstract
In order to report the clinical characteristics and potential risk factors of COVID-19 Patients in Wuhan Stadium Cabin Hospital in Hubei Province. A total of 571 patients of COVID-19 treated in the Wuhan Stadium Cabin Hospital were selected for analysis, univariable and multivariable logistic regression methods were used to explore the risk factors associated with disease aggravation. The main clinical symptoms of moderate COVID-19 were fever, cough and dyspnea, hypertension, diabetes and coronary heart diseases were the main comorbidities both in transferred and stable patients. 26 patients (4.55%) of mild and moderate patients had disease aggravation, and most of which occurred between 36 hours to 48 hours after admission. Multiple regression analysis showed increasing odds of disease aggravation associated with former smoker history, diabetes, dyspnea, consolidation and interstitial abnormalities of CT scanning, lymphopenia and elevated of CRP, the time points of transferred patients mainly between 36 hours to 48 hours (65.38%), and the average hospital stay for stable patients was 15 days.It could help clinicians to identify patients with poor prognosis at an early stage, and provide early warning role for timely intervention. This article is protected by copyright. All rights reserved.
Keywords: Coronavirus disease-19 (COVID-19); clinical characteristics; logistic regression; pneumonia.
. 2020 Aug 11.
doi: 10.1002/jmv.26414. Online ahead of print.
Clinical Characteristics of Moderate COVID-19 Patients Aggravation in Wuhan Stadium Cabin Hospital: A 571 Cases of Retrospective Cohort Study
Lei Shu[SUP] 1 2 [/SUP], Xiaoyan Wang[SUP] 3 [/SUP], Mingquan Li[SUP] 4 [/SUP], Xiaolin Chen[SUP] 1 [/SUP], Ningfei Ji[SUP] 5 [/SUP], Lei Shi[SUP] 1 [/SUP], Mingjing Wu[SUP] 1 [/SUP], Kaili Deng[SUP] 1 [/SUP], Jing Wei[SUP] 1 [/SUP], Xueli Wang[SUP] 1 [/SUP], Yang Cao[SUP] 1 [/SUP], Jiaxin Yan[SUP] 1 [/SUP], Ganzhu Feng[SUP] 6 [/SUP]
Affiliations
- PMID: 32779760
- DOI: 10.1002/jmv.26414
Abstract
In order to report the clinical characteristics and potential risk factors of COVID-19 Patients in Wuhan Stadium Cabin Hospital in Hubei Province. A total of 571 patients of COVID-19 treated in the Wuhan Stadium Cabin Hospital were selected for analysis, univariable and multivariable logistic regression methods were used to explore the risk factors associated with disease aggravation. The main clinical symptoms of moderate COVID-19 were fever, cough and dyspnea, hypertension, diabetes and coronary heart diseases were the main comorbidities both in transferred and stable patients. 26 patients (4.55%) of mild and moderate patients had disease aggravation, and most of which occurred between 36 hours to 48 hours after admission. Multiple regression analysis showed increasing odds of disease aggravation associated with former smoker history, diabetes, dyspnea, consolidation and interstitial abnormalities of CT scanning, lymphopenia and elevated of CRP, the time points of transferred patients mainly between 36 hours to 48 hours (65.38%), and the average hospital stay for stable patients was 15 days.It could help clinicians to identify patients with poor prognosis at an early stage, and provide early warning role for timely intervention. This article is protected by copyright. All rights reserved.
Keywords: Coronavirus disease-19 (COVID-19); clinical characteristics; logistic regression; pneumonia.