tetano
Editor, Senior Moderator
J Med Virol
. 2022 Jul 13.
doi: 10.1002/jmv.27997. Online ahead of print.
Clinical characteristics and outcomes of healthcare workers with COVID-19 pre- and post-vaccination
Fábio Fernandes Dantas Filho[SUP] 1 2 [/SUP], Eunice Beatriz Martin Chaves[SUP] 2 [/SUP], Karen Gomes D'Avila[SUP] 1 2 [/SUP], Jeruza Lavanholi Neyeloff[SUP] 2 [/SUP], Rodrigo Pires Dos Santos[SUP] 2 [/SUP], Denise Rossato Silva[SUP] 1 2 3 [/SUP]
Affiliations
Abstract
Background: Vaccines are the most effective strategy to control the spread of COVID-19. Data on COVID-19 among HCW pre- and post-vaccination are limited. This study aims to evaluate the clinical characteristics and outcomes of HCW with COVID-19 pre- and post-vaccination.
Methods: Retrospective cohort study. All HCWs with suspected COVID-19 were included. Demographic data, occupation, symptoms, work in COVID-19 area, and vaccination status were collected.
Results: There were 22,267 HCW visits for suspected COVID-19; 7,879 (35.4%) tested positive, and 14,388 (64.6%) tested negative. Fever, cough, fatigue, and dyspnea were positive predictors of COVID-19, and sore throat, headache, coryza, work in a COVID-19 area, and COVID-19 vaccination were negative predictors. Of the total number of visits, 41.2% were from vaccinated HCW and 58.8% were from unvaccinated HCW. Among HCWs with COVID-19, 84 (1.1%) required hospitalization, 11 (0.1%) in an intensive care unit (ICU), with three (0.04%) deaths. Six hospitalizations occurred in vaccinated HCWs, being of short duration, with no need for ICU admission and no deaths.
Conclusions: SARS-CoV-2 infection prevalence was high among HCW, and vaccinated HCW had fewer hospitalizations, need for ICU, and deaths. Therefore, vaccines may attenuate COVID-19 severity, and efforts must be concentrated to ensure adequate vaccination for HCW. This article is protected by copyright. All rights reserved.
Keywords: COVID-19; SARS-CoV-2 infection; coronavirus; healthcare workers; hospitalization.; vaccination.
. 2022 Jul 13.
doi: 10.1002/jmv.27997. Online ahead of print.
Clinical characteristics and outcomes of healthcare workers with COVID-19 pre- and post-vaccination
Fábio Fernandes Dantas Filho[SUP] 1 2 [/SUP], Eunice Beatriz Martin Chaves[SUP] 2 [/SUP], Karen Gomes D'Avila[SUP] 1 2 [/SUP], Jeruza Lavanholi Neyeloff[SUP] 2 [/SUP], Rodrigo Pires Dos Santos[SUP] 2 [/SUP], Denise Rossato Silva[SUP] 1 2 3 [/SUP]
Affiliations
- PMID: 35831246
- DOI: 10.1002/jmv.27997
Abstract
Background: Vaccines are the most effective strategy to control the spread of COVID-19. Data on COVID-19 among HCW pre- and post-vaccination are limited. This study aims to evaluate the clinical characteristics and outcomes of HCW with COVID-19 pre- and post-vaccination.
Methods: Retrospective cohort study. All HCWs with suspected COVID-19 were included. Demographic data, occupation, symptoms, work in COVID-19 area, and vaccination status were collected.
Results: There were 22,267 HCW visits for suspected COVID-19; 7,879 (35.4%) tested positive, and 14,388 (64.6%) tested negative. Fever, cough, fatigue, and dyspnea were positive predictors of COVID-19, and sore throat, headache, coryza, work in a COVID-19 area, and COVID-19 vaccination were negative predictors. Of the total number of visits, 41.2% were from vaccinated HCW and 58.8% were from unvaccinated HCW. Among HCWs with COVID-19, 84 (1.1%) required hospitalization, 11 (0.1%) in an intensive care unit (ICU), with three (0.04%) deaths. Six hospitalizations occurred in vaccinated HCWs, being of short duration, with no need for ICU admission and no deaths.
Conclusions: SARS-CoV-2 infection prevalence was high among HCW, and vaccinated HCW had fewer hospitalizations, need for ICU, and deaths. Therefore, vaccines may attenuate COVID-19 severity, and efforts must be concentrated to ensure adequate vaccination for HCW. This article is protected by copyright. All rights reserved.
Keywords: COVID-19; SARS-CoV-2 infection; coronavirus; healthcare workers; hospitalization.; vaccination.