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J Med Virol. Asymptomatic COVID-19 Infection in Late Pregnancy Indicated No Vertical Transmission

tetano

Editor, Senior Moderator
J Med Virol. 2020 Apr 24.
doi: 10.1002/jmv.25927. Online ahead of print.
Asymptomatic COVID-19 Infection in Late Pregnancy Indicated No Vertical Transmission


Dawei Lu[SUP] 1 [/SUP], Lin Sang[SUP] 1 [/SUP], Shihua Du[SUP] 1 [/SUP], Tao Li[SUP] 1 [/SUP], Yange Chang[SUP] 2 [/SUP], Xiu-An Yang[SUP] 2 [/SUP]



Affiliations

Abstract

Objective: This study is to investigate the clinical characteristics of late pregnancy with asymptomatic 2019 novel coronavirus disease (COVID-19) infection, evaluate the outcome of maternal and fetal prognosis, and identify the evidence of intrauterine vertical transmission.
Methods: A 22 years old pregnant woman with asymptomatic COVID-19 infection who was admitted to our hospital on Feb 11, 2020 was enrolled in this study. Clinical data including laboratory test results and chest computed tomography (CT) scanning were collected and reviewed.
Results: Diagnosis of late pregnancy with asymptomatic COVID-19 infection was made. Lumbar anesthesia for cesarean section was performed and a female baby was delivered uneventfully, with the Apgar score of 9-10 points. Three times of COVID-19 nucleic acid test for the baby was negative after delivery. The puerpera returned to normal after the operation and two times of throat swab COVID-19 nucleic acid test were all negative after antiviral therapy.
Conclusion: We reported an asymptomatic COVID-19 pregnant woman with detailed clinical information and our result indicated that for late pregnant women with asymptomatic COVID-19 infection, there might be no intrauterine infection caused by vertical transmission. This article is protected by copyright. All rights reserved.

Keywords: asymptomatic COVID-19 infection; intrauterine infection; late pregnancy; vertical transmission.
 
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