tetano
Editor, Senior Moderator
J Med Virol
. 2024 Sep;96(9):e29862.
doi: 10.1002/jmv.29862. Antibody responses to common viruses according to COVID-19 severity and postacute sequelae of COVID-19
Marianna Karachaliou[SUP] 1 [/SUP], Otavio Ranzani[SUP] 1 [/SUP], Ana Espinosa[SUP] 1 2 3 4 [/SUP], Susana Iraola-Guzmán[SUP] 5 [/SUP], Gemma Castaño-Vinyals[SUP] 1 2 3 4 [/SUP], Marta Vidal[SUP] 1 [/SUP], Alfons Jiménez[SUP] 1 [/SUP], Marc Bañuls[SUP] 1 [/SUP], Eva Alonso Nogués[SUP] 6 [/SUP], Ruth Aguilar[SUP] 1 [/SUP], Judith Garcia-Aymerich[SUP] 1 2 3 [/SUP], Rafael de Cid[SUP] 5 [/SUP], Carlota Dobaño[SUP] 1 7 [/SUP], Gemma Moncunill[SUP] 1 7 [/SUP], Manolis Kogevinas[SUP] 1 2 3 4 [/SUP]
Affiliations
Limited research suggests that certain viruses reactivate in severe-acute-respiratory-syndrome-coronavirus 2 infection, contributing to the development of postacute sequelae of COVID-19 (PASC). We examined 1083 infected individuals from a population-based cohort, and assessed differences in plasma immunoglobulin (Ig)G and immunoglobulin A levels against Epstein-Barr virus (EBV), cytomegalovirus, varicella zoster virus (VZV), BK polyomavirus, KI polyomavirus, WU polyomavirus (WUPyV), respiratory syncytial virus, and Adv-36 according to the severity of previous COVID-19 and PASC history. Individuals who had experienced severe COVID-19 had higher antibody responses to latent viruses. Ever PASC, active persistent PASC, and PASC with neuropsychiatric symptoms were associated with higher immnoglobulin G to EBV early antigen-diffuse, VZV, and WUPyV even among individuals without previous severe COVID-19.
Keywords: COVID‐19; herpesviruses; long COVID; polyomaviruses; postacute sequelae of COVID‐19.
. 2024 Sep;96(9):e29862.
doi: 10.1002/jmv.29862. Antibody responses to common viruses according to COVID-19 severity and postacute sequelae of COVID-19
Marianna Karachaliou[SUP] 1 [/SUP], Otavio Ranzani[SUP] 1 [/SUP], Ana Espinosa[SUP] 1 2 3 4 [/SUP], Susana Iraola-Guzmán[SUP] 5 [/SUP], Gemma Castaño-Vinyals[SUP] 1 2 3 4 [/SUP], Marta Vidal[SUP] 1 [/SUP], Alfons Jiménez[SUP] 1 [/SUP], Marc Bañuls[SUP] 1 [/SUP], Eva Alonso Nogués[SUP] 6 [/SUP], Ruth Aguilar[SUP] 1 [/SUP], Judith Garcia-Aymerich[SUP] 1 2 3 [/SUP], Rafael de Cid[SUP] 5 [/SUP], Carlota Dobaño[SUP] 1 7 [/SUP], Gemma Moncunill[SUP] 1 7 [/SUP], Manolis Kogevinas[SUP] 1 2 3 4 [/SUP]
Affiliations
- PMID: 39247972
- DOI: 10.1002/jmv.29862
Limited research suggests that certain viruses reactivate in severe-acute-respiratory-syndrome-coronavirus 2 infection, contributing to the development of postacute sequelae of COVID-19 (PASC). We examined 1083 infected individuals from a population-based cohort, and assessed differences in plasma immunoglobulin (Ig)G and immunoglobulin A levels against Epstein-Barr virus (EBV), cytomegalovirus, varicella zoster virus (VZV), BK polyomavirus, KI polyomavirus, WU polyomavirus (WUPyV), respiratory syncytial virus, and Adv-36 according to the severity of previous COVID-19 and PASC history. Individuals who had experienced severe COVID-19 had higher antibody responses to latent viruses. Ever PASC, active persistent PASC, and PASC with neuropsychiatric symptoms were associated with higher immnoglobulin G to EBV early antigen-diffuse, VZV, and WUPyV even among individuals without previous severe COVID-19.
Keywords: COVID‐19; herpesviruses; long COVID; polyomaviruses; postacute sequelae of COVID‐19.