tetano
Editor, Senior Moderator
J Med Virol
. 2022 Jun 2.
doi: 10.1002/jmv.27909. Online ahead of print.
Antibody Response Three Months After SARS-CoV-2 Infection
Efdal Oktay Gultekin[SUP] 1 [/SUP], Onur Gultekin[SUP] 2 [/SUP], Arzu Coskun[SUP] 1 [/SUP], Tiince Aksak[SUP] 1 [/SUP]
Affiliations
Abstract
The Coronavirus disease-19 (COVID-19) pandemic became the greatest public health challenge globally. In our study, it was aimed to determine the antibody levels in the 3rd month after the COVID-19 infection and the symptoms that continued until the 3rd month from the onset of the infection. One hundred people who applied to Tarsus State Hospital with the suspicion of COVID-19 and were positive for SARS-CoV-2 infection by real-time reverse transcriptase-polymerase chain reaction (RT-qPCR) were included. We collected serum samples from individuals, who were three months post-infection, and tested them in Anti-SARS-CoV-2 Quanti-Vac ELISA IgG (Euroimmun, Lubeck, Germany) kit coated with recombinant S1 antigen for testing SARS-CoV-2 antibodies. Antibody levels were found to be higher in those aged ≥55 years, non-smokers, those with comorbidities, and those who were hospitalized. The four most common symptoms that individuals initially encounter; are weakness, muscle and joint pain, loss of taste and smell, and cough. In three months after COVID-19 infection, the most common four symptoms are; muscle and joint pain, insomnia, fatigue, and other problems were determined. In conclusion; more research is needed to determine threshold levels of serum antibodies that could prevent reinfection of SARS-CoV-2. This article is protected by copyright. All rights reserved.
Keywords: Immune responses; Immunoglobulin; Infection; SARS coronavirus; Virus classification.
. 2022 Jun 2.
doi: 10.1002/jmv.27909. Online ahead of print.
Antibody Response Three Months After SARS-CoV-2 Infection
Efdal Oktay Gultekin[SUP] 1 [/SUP], Onur Gultekin[SUP] 2 [/SUP], Arzu Coskun[SUP] 1 [/SUP], Tiince Aksak[SUP] 1 [/SUP]
Affiliations
- PMID: 35655391
- DOI: 10.1002/jmv.27909
Abstract
The Coronavirus disease-19 (COVID-19) pandemic became the greatest public health challenge globally. In our study, it was aimed to determine the antibody levels in the 3rd month after the COVID-19 infection and the symptoms that continued until the 3rd month from the onset of the infection. One hundred people who applied to Tarsus State Hospital with the suspicion of COVID-19 and were positive for SARS-CoV-2 infection by real-time reverse transcriptase-polymerase chain reaction (RT-qPCR) were included. We collected serum samples from individuals, who were three months post-infection, and tested them in Anti-SARS-CoV-2 Quanti-Vac ELISA IgG (Euroimmun, Lubeck, Germany) kit coated with recombinant S1 antigen for testing SARS-CoV-2 antibodies. Antibody levels were found to be higher in those aged ≥55 years, non-smokers, those with comorbidities, and those who were hospitalized. The four most common symptoms that individuals initially encounter; are weakness, muscle and joint pain, loss of taste and smell, and cough. In three months after COVID-19 infection, the most common four symptoms are; muscle and joint pain, insomnia, fatigue, and other problems were determined. In conclusion; more research is needed to determine threshold levels of serum antibodies that could prevent reinfection of SARS-CoV-2. This article is protected by copyright. All rights reserved.
Keywords: Immune responses; Immunoglobulin; Infection; SARS coronavirus; Virus classification.