tetano
Editor, Senior Moderator
J Med Virol. 2020 Mar 19. doi: 10.1002/jmv.25773. [Epub ahead of print]
A doubt of multiple introduction of SARS-CoV-2 in Italy: a preliminary overview.
Giovanetti M[SUP]1,[/SUP][SUP]2[/SUP], Angeletti S[SUP]3[/SUP], Benvenuto D[SUP]4[/SUP], Ciccozzi M[SUP]4[/SUP].
Author information
Abstract
The emergence of the novel beta Coronavirus, recently renamed as severe acute respiratory syndrome coronavirus 2, SARS-CoV-2, has raised serious concerns due to the virus rapid dissemination worldwide. Nevertheless, there is limited information about the genomic epidemiology of SARS-CoV-2 circulating in Italy from surveillance studies. The shortage of complete genomic sequences available impairs our understanding of the SARS-CoV-2 introduction and establishment in the country. To better understand its dynamics in Italy, we analysed complete genomes of SARS-CoV-2 isolates, obtained directly from clinical samples. Our phylogenetic reconstructions suggest possible multiple introduction of SARS-CoV-2. Continued genomic surveillance strategies are needed to improve monitoring and understanding of the currently SARS-CoV-2 epidemics, which might help to attenuate public health impact of infectious diseases. This article is protected by copyright. All rights reserved.
This article is protected by copyright. All rights reserved.
KEYWORDS:
COVID-2019; Italian outbreak; phylogenetic inference
PMID:32190908DOI:10.1002/jmv.25773
A doubt of multiple introduction of SARS-CoV-2 in Italy: a preliminary overview.
Giovanetti M[SUP]1,[/SUP][SUP]2[/SUP], Angeletti S[SUP]3[/SUP], Benvenuto D[SUP]4[/SUP], Ciccozzi M[SUP]4[/SUP].
Author information
Abstract
The emergence of the novel beta Coronavirus, recently renamed as severe acute respiratory syndrome coronavirus 2, SARS-CoV-2, has raised serious concerns due to the virus rapid dissemination worldwide. Nevertheless, there is limited information about the genomic epidemiology of SARS-CoV-2 circulating in Italy from surveillance studies. The shortage of complete genomic sequences available impairs our understanding of the SARS-CoV-2 introduction and establishment in the country. To better understand its dynamics in Italy, we analysed complete genomes of SARS-CoV-2 isolates, obtained directly from clinical samples. Our phylogenetic reconstructions suggest possible multiple introduction of SARS-CoV-2. Continued genomic surveillance strategies are needed to improve monitoring and understanding of the currently SARS-CoV-2 epidemics, which might help to attenuate public health impact of infectious diseases. This article is protected by copyright. All rights reserved.
This article is protected by copyright. All rights reserved.
KEYWORDS:
COVID-2019; Italian outbreak; phylogenetic inference
PMID:32190908DOI:10.1002/jmv.25773