tetano
Editor, Senior Moderator
J Med Case Rep
. 2022 Mar 25;16(1):127.
doi: 10.1186/s13256-022-03350-6.
Herpetic anterior uveitis following Pfizer-BioNTech coronavirus disease 2019 vaccine: two case reports
José Manuel Ortiz-Egea[SUP] 1 [/SUP], Cristina Gómez Sánchez[SUP] 2 [/SUP], Andrés López-Jiménez[SUP] 3 [/SUP], Olga Diego Navarro[SUP] 2 [/SUP]
Affiliations
Abstract
Purpose: To describe two cases of herpetic anterior uveitis after inoculation of the first dose of Pfizer-BioNTech coronavirus disease 2019 vaccine.
Methods: Case 1: a healthy 92-year-old Caucasian woman developed symptomatic unilateral anterior uveitis for 3 days after Pfizer-BioNTech coronavirus disease 2019 vaccination (Pfizer Inc.). The episode fully resolved with topical and oral antiviral treatment. Case 2: a previously healthy 85-year-old Caucasian woman with left hemicranial signs of herpes zoster infection, associated with herpetic keratouveitis for 3 days after Pfizer-BioNTech coronavirus disease 2019 vaccination. Treatment with topical antibiotics and both oral and topical antiherpetic medication was administered, and she recovered successfully in 5 weeks.
Conclusion: Clinicians should be aware of the possibility of eye inflammation in the form of herpetic reactivation after coronavirus disease 2019 vaccination.
Keywords: COVID-19 vaccines; Herpes zoster; Inflammation; SARS-CoV2; Uveitis anterior.
. 2022 Mar 25;16(1):127.
doi: 10.1186/s13256-022-03350-6.
Herpetic anterior uveitis following Pfizer-BioNTech coronavirus disease 2019 vaccine: two case reports
José Manuel Ortiz-Egea[SUP] 1 [/SUP], Cristina Gómez Sánchez[SUP] 2 [/SUP], Andrés López-Jiménez[SUP] 3 [/SUP], Olga Diego Navarro[SUP] 2 [/SUP]
Affiliations
- PMID: 35337364
- DOI: 10.1186/s13256-022-03350-6
Abstract
Purpose: To describe two cases of herpetic anterior uveitis after inoculation of the first dose of Pfizer-BioNTech coronavirus disease 2019 vaccine.
Methods: Case 1: a healthy 92-year-old Caucasian woman developed symptomatic unilateral anterior uveitis for 3 days after Pfizer-BioNTech coronavirus disease 2019 vaccination (Pfizer Inc.). The episode fully resolved with topical and oral antiviral treatment. Case 2: a previously healthy 85-year-old Caucasian woman with left hemicranial signs of herpes zoster infection, associated with herpetic keratouveitis for 3 days after Pfizer-BioNTech coronavirus disease 2019 vaccination. Treatment with topical antibiotics and both oral and topical antiherpetic medication was administered, and she recovered successfully in 5 weeks.
Conclusion: Clinicians should be aware of the possibility of eye inflammation in the form of herpetic reactivation after coronavirus disease 2019 vaccination.
Keywords: COVID-19 vaccines; Herpes zoster; Inflammation; SARS-CoV2; Uveitis anterior.