tetano
Editor, Senior Moderator
J Matern Fetal Neonatal Med
. 2020 Aug 30;1-3.
doi: 10.1080/14767058.2020.1811669. Online ahead of print.
Study of amniotic fluid in pregnant women infected with SARS-CoV-2 in first and second trimester. Is there evidence of vertical transmission?
Ana M Rubio Lorente[SUP] 1 [/SUP], Maria Pola Guill?n[SUP] 1 [/SUP], Nuria L?pez Jimenez[SUP] 1 [/SUP], Maria Moreno-Cid Garcia-Suelto[SUP] 1 [/SUP], Eduardo Rodriguez Rodriguez[SUP] 1 [/SUP], Ana Pascual Pedre?o[SUP] 1 [/SUP]
Affiliations
Abstract
COVID-19 is a respiratory disease caused by Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The effects of this infection on fetal development and whether there is vertical transmission are currently unknown. We present two cases of pregnant women with COVID-19 infection during the first and second trimester of gestation in which a PCR study of SARS-CoV-2 in amniotic fluid extracted by amniocentesis is performed to try to determine if there is vertical transmission. In both cases, the PCR result was negative. This fact could support the absence of vertical transmission when the infection occurs in these quarters. It would be advisable to carry out more extensive studies to be able to make this statement safely.
Keywords: COVID-19; amniocentesis; amniotic fluid; pregnancy; vertical transmission.
. 2020 Aug 30;1-3.
doi: 10.1080/14767058.2020.1811669. Online ahead of print.
Study of amniotic fluid in pregnant women infected with SARS-CoV-2 in first and second trimester. Is there evidence of vertical transmission?
Ana M Rubio Lorente[SUP] 1 [/SUP], Maria Pola Guill?n[SUP] 1 [/SUP], Nuria L?pez Jimenez[SUP] 1 [/SUP], Maria Moreno-Cid Garcia-Suelto[SUP] 1 [/SUP], Eduardo Rodriguez Rodriguez[SUP] 1 [/SUP], Ana Pascual Pedre?o[SUP] 1 [/SUP]
Affiliations
- PMID: 32862730
- DOI: 10.1080/14767058.2020.1811669
Abstract
COVID-19 is a respiratory disease caused by Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The effects of this infection on fetal development and whether there is vertical transmission are currently unknown. We present two cases of pregnant women with COVID-19 infection during the first and second trimester of gestation in which a PCR study of SARS-CoV-2 in amniotic fluid extracted by amniocentesis is performed to try to determine if there is vertical transmission. In both cases, the PCR result was negative. This fact could support the absence of vertical transmission when the infection occurs in these quarters. It would be advisable to carry out more extensive studies to be able to make this statement safely.
Keywords: COVID-19; amniocentesis; amniotic fluid; pregnancy; vertical transmission.