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J Korean Med Sci . Risk Factors Related to COVID-19 Reinfection and Fatality During the Omicron (BA.1/BA.2) Period in Korea

tetano

Editor, Senior Moderator
J Korean Med Sci


. 2023 Aug 28;38(34):e269.
doi: 10.3346/jkms.2023.38.e269. Risk Factors Related to COVID-19 Reinfection and Fatality During the Omicron (BA.1/BA.2) Period in Korea

Ju Hee Lee[SUP] 1 [/SUP], Ji Hae Hwang[SUP] 1 [/SUP], Eun Jung Jang[SUP] 1 [/SUP], Ryu Kyung Kim[SUP] 1 [/SUP], Kil Hun Lee[SUP] 1 [/SUP], Seon Kyeong Park[SUP] 1 [/SUP], Jin Gwack[SUP] 2 [/SUP], Young Joon Park[SUP] 3 [/SUP]



Affiliations
Abstract

Background: This study aimed to investigate the deaths due to coronavirus disease 2019 (COVID-19) reinfection and related risk factors.
Methods: National cohort data were collected for a six-month period when omicron BA.1/BA.2 variant was dominant in South Korea.
Results: The long-term care facility residents (adjusted odds ratio, 3.11; 95% confidence interval [CI], 2.98-3.25) had significantly higher risk of reinfection than the general population. The risk of reinfection was significantly lower for persons with 2 or more vaccine doses compared to the unvaccinated. The risk of death was significantly higher in the reinfection group than in the primary infection group for persons in the 60-74 years age group (adjusted relative risk [aRR], 1.62; 95% CI, 1.19-2.20), and immunocompromised group (aRR, 4.56; 95% CI, 2.34-8.90).
Conclusion: In these data, vaccination history was significantly related to reduced COVID-19 reinfection and severe progression, and scheduled vaccinations were important even with a history of infection.

Keywords: COVID-19; Death; Reinfection; SARS-CoV-2; SARS-CoV-2 Omicron Variant.

 
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