tetano
Editor, Senior Moderator
J Korean Med Sci
. 2023 Dec 11;38(48):e382.
doi: 10.3346/jkms.2023.38.e382. Eosinophilic Granulomatosis With Polyangiitis Following COVID-19 Vaccination: A Case Report
Yu-Kyoung Hwang[SUP] 1 [/SUP], Hui-Hwan Kwak[SUP] 1 [/SUP], Jeong-Eun Yun[SUP] 1 [/SUP], Sae-Hoon Kim[SUP] 1 2 [/SUP], Yoon-Seok Chang[SUP] 1 3 [/SUP]
Affiliations
The current emergence of the coronavirus disease 2019 (COVID-19) pandemic and the possible side effects of COVID-19 mRNA vaccination remain worrisome. Few cases of vaccination-related side effects, such as vasculitis, have been reported. Eosinophilic granulomatosis with polyangiitis (EGPA), also known as Churg-Strauss syndrome, is a type of vasculitis characterized by the histological richness of eosinophils, asthma, polyneuropathy, sinusitis, and skin or lung involvement. Here, we report the first case of new onset EGPA following COVID-19 vaccination in Korea. A 71-year old woman developed a skin rash and presented with progressive weakness of the upper and lower extremities after the BNT162b2 vaccination (Pfizer-BioNTech). She was diagnosed with EGPA and her symptoms improved after systemic steroid and immunosuppressant therapy. Although it is very rare, clinicians should be aware that EGPA may occur after COVID-19 vaccination.
Keywords: COVID-19; Churg-Strauss Syndrome; Vaccination.
. 2023 Dec 11;38(48):e382.
doi: 10.3346/jkms.2023.38.e382. Eosinophilic Granulomatosis With Polyangiitis Following COVID-19 Vaccination: A Case Report
Yu-Kyoung Hwang[SUP] 1 [/SUP], Hui-Hwan Kwak[SUP] 1 [/SUP], Jeong-Eun Yun[SUP] 1 [/SUP], Sae-Hoon Kim[SUP] 1 2 [/SUP], Yoon-Seok Chang[SUP] 1 3 [/SUP]
Affiliations
- PMID: 38084026
- DOI: 10.3346/jkms.2023.38.e382
The current emergence of the coronavirus disease 2019 (COVID-19) pandemic and the possible side effects of COVID-19 mRNA vaccination remain worrisome. Few cases of vaccination-related side effects, such as vasculitis, have been reported. Eosinophilic granulomatosis with polyangiitis (EGPA), also known as Churg-Strauss syndrome, is a type of vasculitis characterized by the histological richness of eosinophils, asthma, polyneuropathy, sinusitis, and skin or lung involvement. Here, we report the first case of new onset EGPA following COVID-19 vaccination in Korea. A 71-year old woman developed a skin rash and presented with progressive weakness of the upper and lower extremities after the BNT162b2 vaccination (Pfizer-BioNTech). She was diagnosed with EGPA and her symptoms improved after systemic steroid and immunosuppressant therapy. Although it is very rare, clinicians should be aware that EGPA may occur after COVID-19 vaccination.
Keywords: COVID-19; Churg-Strauss Syndrome; Vaccination.