tetano
Editor, Senior Moderator
J Korean Med Sci
. 2021 Apr 12;36(14):e101.
doi: 10.3346/jkms.2021.36.e101.
Clinical Application of the Standard Q COVID-19 Ag Test for the Detection of SARS-CoV-2 Infection
Sang Min Oh[SUP] 1 [/SUP], Hyeonju Jeong[SUP] 1 [/SUP], Euijin Chang[SUP] 1 [/SUP], Pyoeng Gyun Choe[SUP] 1 [/SUP], Chang Kyung Kang[SUP] 1 [/SUP], Wan Beom Park[SUP] 1 [/SUP], Taek Soo Kim[SUP] 2 [/SUP], Woon Yong Kwon[SUP] 3 [/SUP], Myoung Don Oh[SUP] 1 [/SUP], Nam Joong Kim[SUP] 4 [/SUP]
Affiliations
Abstract
We evaluated the Standard Q COVID-19 Ag test for the diagnosis of coronavirus disease 2019 (COVID-19) compared to the reverse transcription-polymerase chain reaction (RT-PCR) test. We applied both tests to patients who were about to be hospitalized, had visited an emergency room, or had been admitted due to COVID-19 confirmed by RT-PCR. Two nasopharyngeal swabs were obtained; one was tested by RT-PCR and the other by the Standard Q COVID-19 Ag test. A total of 118 pairs of tests from 98 patients were performed between January 5 and 11, 2021. The overall sensitivity and specificity for detecting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) for the Standard Q COVID-19 Ag test compared to RT-PCR were 17.5% (95% confidence interval [CI], 8.8-32.0%) and 100% (95% CI, 95.3-100.0%). Analysis of the results using RT-PCR cycle thresholds of ? 30 or ? 25 increased the sensitivity to 26.9% (95% CI, 13.7-46.1%), and 41.1% (95% CI, 21.6-64.0%), respectively.
Keywords: Antigen Test; COVID-19; SARS-CoV-2.
. 2021 Apr 12;36(14):e101.
doi: 10.3346/jkms.2021.36.e101.
Clinical Application of the Standard Q COVID-19 Ag Test for the Detection of SARS-CoV-2 Infection
Sang Min Oh[SUP] 1 [/SUP], Hyeonju Jeong[SUP] 1 [/SUP], Euijin Chang[SUP] 1 [/SUP], Pyoeng Gyun Choe[SUP] 1 [/SUP], Chang Kyung Kang[SUP] 1 [/SUP], Wan Beom Park[SUP] 1 [/SUP], Taek Soo Kim[SUP] 2 [/SUP], Woon Yong Kwon[SUP] 3 [/SUP], Myoung Don Oh[SUP] 1 [/SUP], Nam Joong Kim[SUP] 4 [/SUP]
Affiliations
- PMID: 33847084
- DOI: 10.3346/jkms.2021.36.e101
Abstract
We evaluated the Standard Q COVID-19 Ag test for the diagnosis of coronavirus disease 2019 (COVID-19) compared to the reverse transcription-polymerase chain reaction (RT-PCR) test. We applied both tests to patients who were about to be hospitalized, had visited an emergency room, or had been admitted due to COVID-19 confirmed by RT-PCR. Two nasopharyngeal swabs were obtained; one was tested by RT-PCR and the other by the Standard Q COVID-19 Ag test. A total of 118 pairs of tests from 98 patients were performed between January 5 and 11, 2021. The overall sensitivity and specificity for detecting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) for the Standard Q COVID-19 Ag test compared to RT-PCR were 17.5% (95% confidence interval [CI], 8.8-32.0%) and 100% (95% CI, 95.3-100.0%). Analysis of the results using RT-PCR cycle thresholds of ? 30 or ? 25 increased the sensitivity to 26.9% (95% CI, 13.7-46.1%), and 41.1% (95% CI, 21.6-64.0%), respectively.
Keywords: Antigen Test; COVID-19; SARS-CoV-2.