tetano
Editor, Senior Moderator
J Intern Med. 2020 Apr 3. doi: 10.1111/joim.13070. [Epub ahead of print]
Familial hypercholesterolemia and COVID-19: triggering of increased sustained cardiovascular risk.
Vuorio A[SUP]1,[/SUP][SUP]2[/SUP], Watts GF[SUP]3,[/SUP][SUP]4[/SUP], Kovanen PT[SUP]5[/SUP].
Author information
Abstract
Early data from Wuhan, China show that patients with COVID-19 are typically male, aged 40 to 60 years, and about one-third have comorbidities. Moreover, of 138 COVID-19 patients hospitalized in Wuhan and treated in an intensive care unit (ICU), 25% had cardiovascular disease and 58% hypertension; the respective figures for non-ICU-treated COVID-19 patients were 10% and 22% [1]. Based on these early data, a predisposition to acute cardiac complications related to underlying atherosclerotic cardiovascular disease (ASCVD) may significantly increase the severity of COVID-19 in susceptible individuals.
This article is protected by copyright. All rights reserved.
KEYWORDS:
COVID-19; PCSK9 inhibitors; atherosclerosis; cardiovascular disease; coronavirus; statins
PMID:32242993DOI:10.1111/joim.13070
Familial hypercholesterolemia and COVID-19: triggering of increased sustained cardiovascular risk.
Vuorio A[SUP]1,[/SUP][SUP]2[/SUP], Watts GF[SUP]3,[/SUP][SUP]4[/SUP], Kovanen PT[SUP]5[/SUP].
Author information
Abstract
Early data from Wuhan, China show that patients with COVID-19 are typically male, aged 40 to 60 years, and about one-third have comorbidities. Moreover, of 138 COVID-19 patients hospitalized in Wuhan and treated in an intensive care unit (ICU), 25% had cardiovascular disease and 58% hypertension; the respective figures for non-ICU-treated COVID-19 patients were 10% and 22% [1]. Based on these early data, a predisposition to acute cardiac complications related to underlying atherosclerotic cardiovascular disease (ASCVD) may significantly increase the severity of COVID-19 in susceptible individuals.
This article is protected by copyright. All rights reserved.
KEYWORDS:
COVID-19; PCSK9 inhibitors; atherosclerosis; cardiovascular disease; coronavirus; statins
PMID:32242993DOI:10.1111/joim.13070