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J Int Med Res . The transmission pattern and clinical course of the first 417 patients with COVID-19 infection in Shenzhen, China

tetano

Editor, Senior Moderator
J Int Med Res


. 2023 May;51(5):3000605231174303.
doi: 10.1177/03000605231174303. The transmission pattern and clinical course of the first 417 patients with COVID-19 infection in Shenzhen, China

Yizi Zheng[SUP] 1 [/SUP], Zhenhan Deng[SUP] 2 [/SUP], Feijuan Huang[SUP] 3 [/SUP], Yu Zhang[SUP] 4 [/SUP], Yuanzhe Cai[SUP] 5 [/SUP], Jingyue Su[SUP] 2 [/SUP], Zhengzhi Wu[SUP] 3 [/SUP], Shiwei Yang[SUP] 6 [/SUP]



Affiliations
Abstract

Objective: To explore the transmission patterns and clinical course of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that was first identified in Wuhan, China in December 2019 as clustered and non-clustered cases of coronavirus disease (COVID-19) emerged in Shenzhen, China.
Methods: This retrospective study included the patients that were confirmed by laboratory detection of SARS-CoV-2 in Shenzen between 19 January 2020 and 21 February 2020. Data on the epidemiological and clinical characteristics were analysed. The patients were divided into non-clustered and clustered groups. The time course, intervals between first and second COVID-19 cases and other transmission patterns were compared between the groups.
Results: The 417 patients were divided into clustered (n = 235) and non-clustered groups (n = 182). Compared with the non-clustered group, the clustered group had significantly more young (≤20 years) and old (>60 years) patients. The clustered group had significantly more severe cases (nine of 235; 3.83%) compared with the non-clustered group (three of 182; 1.65%). Patients with severe disease spent 4-5 more days of hospitalization than patients with moderate and mild disease.
Conclusion: This retrospective study analysed the transmission patterns and clinical course of the first wave of COVID-19 infection in Shenzhen, China.

Keywords: COVID-19; clinical course; clustered; non-clustered; transmission pattern.

 
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