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J Int Med Res . Multifocal motor neuropathy after SARS-CoV-2 vaccination: a causal or coincidental association?

tetano

Editor, Senior Moderator
J Int Med Res


. 2022 Jul;50(7):3000605221110709.
doi: 10.1177/03000605221110709.
Multifocal motor neuropathy after SARS-CoV-2 vaccination: a causal or coincidental association?


Fettah Eren[SUP] 1 [/SUP], Recep Aygul[SUP] 1 [/SUP], Sevde Tenekeci[SUP] 1 [/SUP], Serefnur Ozturk[SUP] 1 [/SUP]



Affiliations

Abstract

Multifocal motor neuropathy (MMN) is an immune-mediated and acquired demyelinating motor polyneuropathy. Several cases of polyneuropathy associated with severe acquired respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination have been reported. However, MMN has not been reported as a complication of SARS-CoV-2 vaccination. In this study, we report a case of MMN with progressive muscle weakness following the second dose of the Pfizer-BioNTech mRNA vaccine. It was diagnosed by clinical evaluation and electroneuromyography. SARS-CoV-2 vaccination is increasing rapidly all over the world. Some cases of polyneuropathy, especially Guillain-Barré syndrome, have been reported after vaccination. This is the first case report of MMN after SARS-CoV-2 vaccination.

Keywords: Motor neuropathy; SARS-CoV-2; coronavirus disease 2019; muscle weakness; polyneuropathy; vaccination.



Fettah Eren[SUP] 1 [/SUP], Recep Aygul[SUP] 1 [/SUP], Sevde Tenekeci[SUP] 1 [/SUP], Serefnur Ozturk[SUP] 1 [/SUP]



Affiliations

Abstract

Multifocal motor neuropathy (MMN) is an immune-mediated and acquired demyelinating motor polyneuropathy. Several cases of polyneuropathy associated with severe acquired respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination have been reported. However, MMN has not been reported as a complication of SARS-CoV-2 vaccination. In this study, we report a case of MMN with progressive muscle weakness following the second dose of the Pfizer-BioNTech mRNA vaccine. It was diagnosed by clinical evaluation and electroneuromyography. SARS-CoV-2 vaccination is increasing rapidly all over the world. Some cases of polyneuropathy, especially Guillain-Barré syndrome, have been reported after vaccination. This is the first case report of MMN after SARS-CoV-2 vaccination.

Keywords: Motor neuropathy; SARS-CoV-2; coronavirus disease 2019; muscle weakness; polyneuropathy; vaccination.
 
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