tetano
Editor, Senior Moderator
J Inflamm Res
. 2022 Nov 2;15:6047-6053.
doi: 10.2147/JIR.S369477. eCollection 2022.
Dermatomyositis Flare After a COVID-19 Infection Successfully Treated with Rituximab: A Case Report and Literature Review
Ahmed Mohammed Albakri[SUP] 1 [/SUP], Ahmed Hussein Subki[SUP] 1 [/SUP], Abdurahman Albeity[SUP] 1 [/SUP], Hussein Halabi[SUP] 1 [/SUP]
Affiliations
Abstract
Introduction: Since the beginning of the coronavirus disease 2019 (COVID-19) pandemic, there has been a sudden surge in the incidence of several immune-mediated diseases, including dermatomyositis. The reported cases of COVID-19-related dermatomyositis are heterogeneous in their clinical presentation and implemented therapies.
Case study: We report a 23-year-old female patient diagnosed with a 3-year history of dermatomyositis. She has been well-controlled on maintenance therapy. However, 6 weeks after a mild COVID-19 infection, she developed a dermatomyositis flare. She improved only after aggressive treatment with pulse steroids, intravenous immunoglobulin, and rituximab.
Conclusion: Exacerbation of dermatomyositis can be encountered following a COVID-19 infection, even if the infection is mild. Aggressive therapy should be considered in such cases. The prognosis, however, is generally favorable.
Keywords: COVID-19 infection; Rituximab; dermatomyositis.
. 2022 Nov 2;15:6047-6053.
doi: 10.2147/JIR.S369477. eCollection 2022.
Dermatomyositis Flare After a COVID-19 Infection Successfully Treated with Rituximab: A Case Report and Literature Review
Ahmed Mohammed Albakri[SUP] 1 [/SUP], Ahmed Hussein Subki[SUP] 1 [/SUP], Abdurahman Albeity[SUP] 1 [/SUP], Hussein Halabi[SUP] 1 [/SUP]
Affiliations
- PMID: 36348728
- PMCID: PMC9637344
- DOI: 10.2147/JIR.S369477
Abstract
Introduction: Since the beginning of the coronavirus disease 2019 (COVID-19) pandemic, there has been a sudden surge in the incidence of several immune-mediated diseases, including dermatomyositis. The reported cases of COVID-19-related dermatomyositis are heterogeneous in their clinical presentation and implemented therapies.
Case study: We report a 23-year-old female patient diagnosed with a 3-year history of dermatomyositis. She has been well-controlled on maintenance therapy. However, 6 weeks after a mild COVID-19 infection, she developed a dermatomyositis flare. She improved only after aggressive treatment with pulse steroids, intravenous immunoglobulin, and rituximab.
Conclusion: Exacerbation of dermatomyositis can be encountered following a COVID-19 infection, even if the infection is mild. Aggressive therapy should be considered in such cases. The prognosis, however, is generally favorable.
Keywords: COVID-19 infection; Rituximab; dermatomyositis.