tetano
Editor, Senior Moderator
J Infect Prev
. 2020 May;21(3):119-121.
doi: 10.1177/1757177420908012. Epub 2020 May 4.
End-of-season Outbreaks of Nosocomial Influenza Caused by Waning Vaccine Immunity
Masahide Matsushita[SUP] 1 [/SUP], Kazumi Arise[SUP] 2 [/SUP], Norihito Morimoto[SUP] 2 3 [/SUP], Seisho Takeuchi[SUP] 2 4 [/SUP]
Affiliations
Abstract
The waning of vaccine protection may be responsible for outbreaks toward the end of the influenza season. Three of five outbreaks occurred at the beginning of April following an interval of >100 days from the date of vaccination; the reported index case was a nurse or office worker, and >50% of those affected were healthcare workers. The results are consistent with intra-seasonal waning of vaccine immunity that resulted in outbreaks at the end of season.
Keywords: Infection control; influenza; outbreak; surveillance; vaccination.
. 2020 May;21(3):119-121.
doi: 10.1177/1757177420908012. Epub 2020 May 4.
End-of-season Outbreaks of Nosocomial Influenza Caused by Waning Vaccine Immunity
Masahide Matsushita[SUP] 1 [/SUP], Kazumi Arise[SUP] 2 [/SUP], Norihito Morimoto[SUP] 2 3 [/SUP], Seisho Takeuchi[SUP] 2 4 [/SUP]
Affiliations
- PMID: 32494296
- PMCID: PMC7238694 (available on 2021-05-01)
- DOI: 10.1177/1757177420908012
Abstract
The waning of vaccine protection may be responsible for outbreaks toward the end of the influenza season. Three of five outbreaks occurred at the beginning of April following an interval of >100 days from the date of vaccination; the reported index case was a nurse or office worker, and >50% of those affected were healthcare workers. The results are consistent with intra-seasonal waning of vaccine immunity that resulted in outbreaks at the end of season.
Keywords: Infection control; influenza; outbreak; surveillance; vaccination.