tetano
Editor, Senior Moderator
J Infect
. 2020 Jul 30;S0163-4453(20)30509-0.
doi: 10.1016/j.jinf.2020.07.028. Online ahead of print.
Magnetic Resonance Imaging of COVID-19 Anosmic Patients Reveals Abnormalities of the Olfactory Bulb: Preliminary Prospective Study
Annaelle Chetrit[SUP] 1 [/SUP], Jerome R Lechien[SUP] 2 [/SUP], Amine Ammar[SUP] 1 [/SUP], Younes Chekkoury-Idrissi[SUP] 3 [/SUP], Lea Distinguin[SUP] 3 [/SUP], Marta Circiu[SUP] 3 [/SUP], Sven Saussez[SUP] 4 [/SUP], Marie-Christine Ballester[SUP] 5 [/SUP], Marc Vasse[SUP] 6 [/SUP], Najete Berradja[SUP] 1 [/SUP], Stephane Hans[SUP] 3 [/SUP], Robert Carlier[SUP] 1 [/SUP], Myriam Edjlali[SUP] 7 [/SUP]
Affiliations
Abstract
•COVID-19 patients with total loss of smell have more olfactory bulb abnormalities at the magnetic resonance imaging than patients without loss of smell.•The olfactory bulb MRI abnormalities may be objectified through a signal intensity ratio measurement that is calculated between the average signals of the olfactory bulb and the frontal white matter.•The loss of smell is probably due to olfactory bulb inflammation related to virus spread.
Keywords: COVID-19; Coronavirus; MRI; anosmia; imaging; olfaction; olfactory; smell.
. 2020 Jul 30;S0163-4453(20)30509-0.
doi: 10.1016/j.jinf.2020.07.028. Online ahead of print.
Magnetic Resonance Imaging of COVID-19 Anosmic Patients Reveals Abnormalities of the Olfactory Bulb: Preliminary Prospective Study
Annaelle Chetrit[SUP] 1 [/SUP], Jerome R Lechien[SUP] 2 [/SUP], Amine Ammar[SUP] 1 [/SUP], Younes Chekkoury-Idrissi[SUP] 3 [/SUP], Lea Distinguin[SUP] 3 [/SUP], Marta Circiu[SUP] 3 [/SUP], Sven Saussez[SUP] 4 [/SUP], Marie-Christine Ballester[SUP] 5 [/SUP], Marc Vasse[SUP] 6 [/SUP], Najete Berradja[SUP] 1 [/SUP], Stephane Hans[SUP] 3 [/SUP], Robert Carlier[SUP] 1 [/SUP], Myriam Edjlali[SUP] 7 [/SUP]
Affiliations
- PMID: 32739489
- PMCID: PMC7392133
- DOI: 10.1016/j.jinf.2020.07.028
Abstract
•COVID-19 patients with total loss of smell have more olfactory bulb abnormalities at the magnetic resonance imaging than patients without loss of smell.•The olfactory bulb MRI abnormalities may be objectified through a signal intensity ratio measurement that is calculated between the average signals of the olfactory bulb and the frontal white matter.•The loss of smell is probably due to olfactory bulb inflammation related to virus spread.
Keywords: COVID-19; Coronavirus; MRI; anosmia; imaging; olfaction; olfactory; smell.