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J Infect Dis . Viral Aetiology of Lower Respiratory Tract Infections in Infants Attending Primary Care in Eastern Spain, 2023-2025

tetano

Editor, Senior Moderator
J Infect Dis

. 2026 Nov 5:jiag543.
doi: 10.1093/infdis/jiag543. Online ahead of print.

Viral Aetiology of Lower Respiratory Tract Infections in Infants Attending Primary Care in Eastern Spain, 2023-2025​


Luca Marcello-Carloni 1 , María Herrero-Silvestre 2 , Chloé Mintsa 3 , Cintia Muñoz-Quiles 2 4 , Mónica López-Lacort 2 4 , Ainara Mira-Iglesias 2 4 , Brenda Marquina-Sánchez 2 , F Xavier López-Labrador 4 5 6 , María Garcés-Sánchez 7 , Begoña Escribano-López 2 , Matilde Zornoza-Moreno 8 , Jaime Jesús Pérez-Martín 8 , Santiago Alfayate-Miguelez 8 , Antonio Iofrío-De Arce 9 , Javier Díez-Domingo 2 4 10 , Alejandro Orrico-Sánchez 2 4 10 ; MEDIPRIM network; the

Collaborators, Affiliations Expand


Abstract​


To describe seasonal patterns of respiratory viruses in infants presenting to primary care (PC) after the rollout of the RSV-immunisation programme in Spain, we analysed multiplex RT-PCR results from infants <1 year with lower respiratory tract infections (LRTIs) attending 57 PC centres in Valencia and Murcia across two seasons. Among the 307 infants, rhinovirus/enterovirus and RSV were the most common detections in both periods. hMPV, bocavirus, and influenza followed. Our findings highlight the importance of community-based surveillance systems for providing real-world evidence to inform future immunisation strategies.

Keywords: RSV; Spain; infants; primary care; respiratory viruses; rhinovirus; seasonal patterns; surveillance systems.
 
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