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J Infect Dis. Human Infection with a Triple-Reassortant Swine Influenza A(H1N1) Virus Containing the Hemagglutinin and Neuraminidase Genes of Seasonal

Giuseppe

Emeritus
Human Infection with a Triple-Reassortant Swine Influenza A(H1N1) Virus Containing the Hemagglutinin and Neuraminidase Genes of Seasonal Influenza Virus. (J Infect Dis., abstract, edited)

10. J Infect Dis. 2010 Feb 23. [Epub ahead of print]

Human Infection with a Triple-Reassortant Swine Influenza A(H1N1) Virus Containing the Hemagglutinin and Neuraminidase Genes of Seasonal Influenza Virus.

Bastien N, Antonishyn NA, Brandt K, Wong CE, Chokani K, Vegh N, Horsman GB, Tyler S, Graham MR, Plummer FA, Levett PN, Li Y. - National Microbiology Laboratory, Public Health Agency of Canada, and 2Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba, and 3Saskatchewan Disease Control Laboratory, Regina, and 4Prince Albert Parkland Health Region, Prince Albert, Saskatchewan, Canada.

A reassortant influenza A(H1N1) virus of swine origin distinct from the pandemic H1N1 2009 strain was isolated from 3 patients, all of whom worked at the same large hog operation in Saskatchewan, Canada. The genomic composition of the isolates has not been previously reported, to our knowledge, and was the product of a genetic reassortment between seasonal H1N1 and triple-reassortant influenza virus that emerged in North American swine during the late 1990s. The neuraminidase and hemagglutinin genes of A/Saskatchewan/5350/2009, A/Saskatchewan/5351/2009, and A/Saskatchewan/5131/2009 were derived from human H1N1 virus and were closely related to those of A/Brisbane/59/2007.

PMID: 20199242 [PubMed - as supplied by publisher]
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