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J Infect Dis . Do pregnant persons want influenza vaccines? Knowledge, attitudes, perceptions, and practices toward influenza vaccines in 8 low- and

tetano

Editor, Senior Moderator
J Infect Dis


. 2024 Jul 2:jiae340.
doi: 10.1093/infdis/jiae340. Online ahead of print. Do pregnant persons want influenza vaccines? Knowledge, attitudes, perceptions, and practices toward influenza vaccines in 8 low- and middle-income countries

Margaret McCarron[SUP] 1 [/SUP], Tat S Yau[SUP] 1 [/SUP], Chelsey Griffin[SUP] 1 [/SUP], Perrine Marcenac[SUP] 1 [/SUP], Malembe S Ebama[SUP] 2 [/SUP], Kathryn E Lafond[SUP] 1 [/SUP], Ledor S Igboh[SUP] 1 [/SUP], Lindsey M Duca[SUP] 1 [/SUP], Silvia Bino[SUP] 3 [/SUP], Jihene Bettaieb[SUP] 4 [/SUP], Sonia Dhaouadi[SUP] 5 [/SUP], Gayane Sahakyan[SUP] 6 [/SUP], Imad Cherkaoui[SUP] 7 [/SUP], Loubna Alj[SUP] 7 [/SUP], Daouda Coulibaly[SUP] 8 [/SUP], Julius J Lutwama[SUP] 9 [/SUP], Alfred Douba[SUP] 8 [/SUP], Anderson N'Gattia[SUP] 8 [/SUP], Viengphone Khanthamaly[SUP] 1 10 [/SUP], Chankham Tengbriacheu[SUP] 10 [/SUP], Chansay Patthammavong[SUP] 10 [/SUP], Philipp Lambach[SUP] 11 [/SUP], Dinagul Otorbaeva[SUP] 12 [/SUP], Eduardo Azziz-Baumgartner[SUP] 1 [/SUP], Joseph S Bresee[SUP] 2 [/SUP]



Affiliations
Abstract

Background: While vaccination is the most effective way to prevent influenza infection and adverse outcomes, and despite WHO recommendations to vaccinate pregnant persons, access to seasonal influenza vaccines remains low. We explored knowledge, attitudes, and practices of pregnant persons about seasonal influenza vaccines to inform actions to improve vaccine uptake among this priority population.
Methods: We pooled individual-level data from cross-sectional surveys assessing pregnant persons' attitudes toward seasonal influenza vaccines in eight low- and middle-income countries during 2018-2019. The eight countries used a standard protocol and questionnaire to measure attitudes and intents toward influenza vaccination. We stratified by country-level (presence/absence of a national influenza vaccination program, country income group, geographic region) and individual-level factors.
Findings: Our analysis included 8,556 pregnant persons from eight low- and middle-income countries with and without seasonal influenza vaccination programs. Most pregnant persons (6,323, 74%) were willing to receive influenza vaccine if it was offered for free. Willingness differed by presence of an existing influenza vaccination program; acceptance was higher in countries without influenza vaccination programs (2,383, 89%) than in those with such programs (3,940, 67%, p < 0.001).
Interpretation: Most pregnant persons in middle-income countries, regardless of influenza vaccination program status, were willing to be vaccinated against influenza if the vaccine was provided free of charge. National investments in influenza vaccination programs may be well-received by pregnant persons, leading to averted illness both in pregnant persons themselves and in their newborn babies.
Funding: US Centers for Disease Control and Prevention.

Keywords: Infectious disease prevention; Influenza; Vaccination.

 
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