tetano
Editor, Senior Moderator
J Infect Dev Ctries
. 2021 Apr 30;15(4):490-500.
doi: 10.3855/jidc.14178.
Nutritional status is closely related to the severity of COVID-19: a multi-center retrospective study
Yang Li[SUP] 1 [/SUP], Chuanwu Zhu[SUP] 2 [/SUP], Biao Zhang[SUP] 3 [/SUP], Longgen Liu[SUP] 4 [/SUP], Fang Ji[SUP] 5 [/SUP], Yun Zhao[SUP] 6 [/SUP], Juan Cheng[SUP] 7 [/SUP], Huaping Shao[SUP] 8 [/SUP], Xinying Guan[SUP] 9 [/SUP], Fang Ming[SUP] 10 [/SUP], Chao Wu[SUP] 11 [/SUP], Zhi Xiang Du[SUP] 12 [/SUP]
Affiliations
Abstract
Introduction: Nutritional status has been defined as an individual's health condition. The relationship between the progression of COVID-19 and Nutritional status is still unclear. We analyzed the clinical characteristics of 342 coronavirus disease 2019 (COVID-19) patients, and analyzed the relationship between the progression of COVID-19 and Nutritional status.
Methodology: 342 COVID-19 were enrolled from ten different hospitals in China. The clinical characteristics were collected and analyzed.
Results: The body mass index (BMI) of the mild patients (Group A) was higher than those in severe patients (Group B) and critical patients (Group C); The lactate dehydrogenase (LDH) level of Group A was lower than those of the other two groups; Sex, age, and BMI, was strongly correlated with Clinical classification (CT); Among the laboratory test results, Neutrophil (NEU%), Aspartate aminotransferase (AST), LDH, and blood glucose (BG) were positively correlated with CT; Lymphocyte ( LYM%), Platelet (PLT), Albumin (ALB), and Creatinine (Cr) were negatively correlated with CT. BMI, NEU%, LYM%, ALB, Cr, and PLT are all protective factors that affect CT.
Conclusion: People with poor nutritional status (lower BMI and ALB) have a higher risk of developing severe disease after infection with SARS-CoV-2. In the clinical treatment of COVID-19, individualized nutritional support is very important for the rehabilitation of patients.
Keywords: ALB; BMI; COVID-19; LDH; Nutritional status.
. 2021 Apr 30;15(4):490-500.
doi: 10.3855/jidc.14178.
Nutritional status is closely related to the severity of COVID-19: a multi-center retrospective study
Yang Li[SUP] 1 [/SUP], Chuanwu Zhu[SUP] 2 [/SUP], Biao Zhang[SUP] 3 [/SUP], Longgen Liu[SUP] 4 [/SUP], Fang Ji[SUP] 5 [/SUP], Yun Zhao[SUP] 6 [/SUP], Juan Cheng[SUP] 7 [/SUP], Huaping Shao[SUP] 8 [/SUP], Xinying Guan[SUP] 9 [/SUP], Fang Ming[SUP] 10 [/SUP], Chao Wu[SUP] 11 [/SUP], Zhi Xiang Du[SUP] 12 [/SUP]
Affiliations
- PMID: 33956648
- DOI: 10.3855/jidc.14178
Abstract
Introduction: Nutritional status has been defined as an individual's health condition. The relationship between the progression of COVID-19 and Nutritional status is still unclear. We analyzed the clinical characteristics of 342 coronavirus disease 2019 (COVID-19) patients, and analyzed the relationship between the progression of COVID-19 and Nutritional status.
Methodology: 342 COVID-19 were enrolled from ten different hospitals in China. The clinical characteristics were collected and analyzed.
Results: The body mass index (BMI) of the mild patients (Group A) was higher than those in severe patients (Group B) and critical patients (Group C); The lactate dehydrogenase (LDH) level of Group A was lower than those of the other two groups; Sex, age, and BMI, was strongly correlated with Clinical classification (CT); Among the laboratory test results, Neutrophil (NEU%), Aspartate aminotransferase (AST), LDH, and blood glucose (BG) were positively correlated with CT; Lymphocyte ( LYM%), Platelet (PLT), Albumin (ALB), and Creatinine (Cr) were negatively correlated with CT. BMI, NEU%, LYM%, ALB, Cr, and PLT are all protective factors that affect CT.
Conclusion: People with poor nutritional status (lower BMI and ALB) have a higher risk of developing severe disease after infection with SARS-CoV-2. In the clinical treatment of COVID-19, individualized nutritional support is very important for the rehabilitation of patients.
Keywords: ALB; BMI; COVID-19; LDH; Nutritional status.