tetano
Editor, Senior Moderator
J Infect Chemother
. 2021 Oct 20;S1341-321X(21)00282-8.
doi: 10.1016/j.jiac.2021.10.013. Online ahead of print.
Fatty liver on computed tomography scan on admission is a risk factor for severe coronavirus disease
Ayako Okuhama[SUP] 1 [/SUP], Masatoshi Hotta[SUP] 2 [/SUP], Masahiro Ishikane[SUP] 3 [/SUP], Akira Kawashima[SUP] 1 [/SUP], Yusuke Miyazato[SUP] 1 [/SUP], Mari Terada[SUP] 4 [/SUP], Gen Yamada[SUP] 1 [/SUP], Kohei Kanda[SUP] 1 [/SUP], Makoto Inada[SUP] 1 [/SUP], Lubna Sato[SUP] 1 [/SUP], Mitsuhiro Sato[SUP] 1 [/SUP], Yutaro Akiyama[SUP] 1 [/SUP], Tetsuya Suzuki[SUP] 1 [/SUP], Takato Nakamoto[SUP] 1 [/SUP], Hidetoshi Nomoto[SUP] 1 [/SUP], Satoshi Ide[SUP] 1 [/SUP], Keiji Nakamura[SUP] 1 [/SUP], Sho Saito[SUP] 1 [/SUP], Noriko Kinoshita[SUP] 1 [/SUP], Kei Yamamoto[SUP] 1 [/SUP], Shinichiro Morioka[SUP] 1 [/SUP], Mugen Ujiie[SUP] 1 [/SUP], Kayoko Hayakawa[SUP] 1 [/SUP], Satoshi Kustuna[SUP] 1 [/SUP], Yoshitaka Shida[SUP] 2 [/SUP], Tsuyoshi Tajima[SUP] 2 [/SUP], Katsuji Teruya[SUP] 5 [/SUP], Yumi Funato[SUP] 6 [/SUP], Makiko Yamamoto[SUP] 6 [/SUP], Shinyu Izumi[SUP] 7 [/SUP], Masayuki Hojo[SUP] 7 [/SUP], Haruhito Sugiyama[SUP] 8 [/SUP], Norio Ohmagari[SUP] 1 [/SUP]
Affiliations
Abstract
Objectives: To alleviate the overflow of coronavirus disease 2019 (COVID-19) patients in hospitals, less invasive and simple criteria are required to triage the patients. We evaluated the relationship between COVID-19 severity and fatty liver on plain computed tomography (CT) scan performed on admission.
Methods: In this retrospective cohort study, we considered all COVID-19 patients at a large tertiary care hospital between January 31 and August 31, 2020. COVID-19 severity was categorized into severe (moderate and severe) and non-severe (asymptomatic and mild) groups, based on the Japanese National COVID-19 guidelines. Fatty liver was detected on plain CT scan. Multivariate logistic regression analysis was performed to evaluate factors associated with severe COVID-19.
Results: Of 222 patients (median age: 52 years), 3.2%, 58.1%, 20.7%, and 18.0% presented with asymptomatic, mild, moderate, and severe COVID-19, respectively. Although 59.9% had no fatty liver on plain CT, mild, moderate, and severe fatty liver occurred in 13.1%, 18.9%, and 8.1%, respectively. Age and presence of fatty liver were significantly associated with severe COVID-19.
Conclusion: Our study showed that fatty liver on plain CT scan on admission can become a risk factor for severe COVID-19. This finding may help clinicians to easily triage COVID-19 patients.
Keywords: COVID-19; Outcome; Pneumonia; Triage.
. 2021 Oct 20;S1341-321X(21)00282-8.
doi: 10.1016/j.jiac.2021.10.013. Online ahead of print.
Fatty liver on computed tomography scan on admission is a risk factor for severe coronavirus disease
Ayako Okuhama[SUP] 1 [/SUP], Masatoshi Hotta[SUP] 2 [/SUP], Masahiro Ishikane[SUP] 3 [/SUP], Akira Kawashima[SUP] 1 [/SUP], Yusuke Miyazato[SUP] 1 [/SUP], Mari Terada[SUP] 4 [/SUP], Gen Yamada[SUP] 1 [/SUP], Kohei Kanda[SUP] 1 [/SUP], Makoto Inada[SUP] 1 [/SUP], Lubna Sato[SUP] 1 [/SUP], Mitsuhiro Sato[SUP] 1 [/SUP], Yutaro Akiyama[SUP] 1 [/SUP], Tetsuya Suzuki[SUP] 1 [/SUP], Takato Nakamoto[SUP] 1 [/SUP], Hidetoshi Nomoto[SUP] 1 [/SUP], Satoshi Ide[SUP] 1 [/SUP], Keiji Nakamura[SUP] 1 [/SUP], Sho Saito[SUP] 1 [/SUP], Noriko Kinoshita[SUP] 1 [/SUP], Kei Yamamoto[SUP] 1 [/SUP], Shinichiro Morioka[SUP] 1 [/SUP], Mugen Ujiie[SUP] 1 [/SUP], Kayoko Hayakawa[SUP] 1 [/SUP], Satoshi Kustuna[SUP] 1 [/SUP], Yoshitaka Shida[SUP] 2 [/SUP], Tsuyoshi Tajima[SUP] 2 [/SUP], Katsuji Teruya[SUP] 5 [/SUP], Yumi Funato[SUP] 6 [/SUP], Makiko Yamamoto[SUP] 6 [/SUP], Shinyu Izumi[SUP] 7 [/SUP], Masayuki Hojo[SUP] 7 [/SUP], Haruhito Sugiyama[SUP] 8 [/SUP], Norio Ohmagari[SUP] 1 [/SUP]
Affiliations
- PMID: 34756574
- DOI: 10.1016/j.jiac.2021.10.013
Abstract
Objectives: To alleviate the overflow of coronavirus disease 2019 (COVID-19) patients in hospitals, less invasive and simple criteria are required to triage the patients. We evaluated the relationship between COVID-19 severity and fatty liver on plain computed tomography (CT) scan performed on admission.
Methods: In this retrospective cohort study, we considered all COVID-19 patients at a large tertiary care hospital between January 31 and August 31, 2020. COVID-19 severity was categorized into severe (moderate and severe) and non-severe (asymptomatic and mild) groups, based on the Japanese National COVID-19 guidelines. Fatty liver was detected on plain CT scan. Multivariate logistic regression analysis was performed to evaluate factors associated with severe COVID-19.
Results: Of 222 patients (median age: 52 years), 3.2%, 58.1%, 20.7%, and 18.0% presented with asymptomatic, mild, moderate, and severe COVID-19, respectively. Although 59.9% had no fatty liver on plain CT, mild, moderate, and severe fatty liver occurred in 13.1%, 18.9%, and 8.1%, respectively. Age and presence of fatty liver were significantly associated with severe COVID-19.
Conclusion: Our study showed that fatty liver on plain CT scan on admission can become a risk factor for severe COVID-19. This finding may help clinicians to easily triage COVID-19 patients.
Keywords: COVID-19; Outcome; Pneumonia; Triage.