tetano
Editor, Senior Moderator
J Infect Chemother
. 2024 Apr 16:S1341-321X(24)00115-6.
doi: 10.1016/j.jiac.2024.04.007. Online ahead of print. Evaluating the Association of Body Mass Index with COVID-19 Severity and Mortality using Japanese Administrative Claims Data
Waki Imoto[SUP] 1 [/SUP], Yasutaka Ihara[SUP] 2 [/SUP], Takumi Imai[SUP] 3 [/SUP], Mitsuhiro Tamoto[SUP] 4 [/SUP], Tatoi Ibuki[SUP] 5 [/SUP], Koichi Yamada[SUP] 6 [/SUP], Yukihiro Kaneko[SUP] 7 [/SUP], Ayumi Shintani[SUP] 8 [/SUP], Hiroshi Kakeya[SUP] 9 [/SUP]
Affiliations
Introduction: Obesity is a risk factor for aggravation of and mortality from coronavirus disease 2019 (COVID-19). We aimed to investigate the relationship between COVID-19 and Body Mass Index (BMI) in the Japanese population.
Methods: We used administrative claims data from an advanced treatment hospital in Japan and extracted data from patients hospitalized for COVID-19. The exposure variable was BMI measured at the time of admission, and the study outcomes were progression to critical illness and death. Analyses were performed for each age group.
Results: Overall, 58,944 patients met the inclusion criteria. The risk of critical illness increased monotonically with higher BMI. In contrast, the relationship between BMI and mortality follows a J-shaped curve; being underweight and obese are risk factors for mortality. When stratified by age, similar trends were observed for both critical illness and mortality.
Conclusion: A higher BMI is a risk factor for the progression of COVID-19 severity, whereas both lower and higher BMIs are risk factors for mortality in the Japanese population.
Keywords: administrative claims database; body mass index; coronavirus disease 2019; obesity.
. 2024 Apr 16:S1341-321X(24)00115-6.
doi: 10.1016/j.jiac.2024.04.007. Online ahead of print. Evaluating the Association of Body Mass Index with COVID-19 Severity and Mortality using Japanese Administrative Claims Data
Waki Imoto[SUP] 1 [/SUP], Yasutaka Ihara[SUP] 2 [/SUP], Takumi Imai[SUP] 3 [/SUP], Mitsuhiro Tamoto[SUP] 4 [/SUP], Tatoi Ibuki[SUP] 5 [/SUP], Koichi Yamada[SUP] 6 [/SUP], Yukihiro Kaneko[SUP] 7 [/SUP], Ayumi Shintani[SUP] 8 [/SUP], Hiroshi Kakeya[SUP] 9 [/SUP]
Affiliations
- PMID: 38636933
- DOI: 10.1016/j.jiac.2024.04.007
Introduction: Obesity is a risk factor for aggravation of and mortality from coronavirus disease 2019 (COVID-19). We aimed to investigate the relationship between COVID-19 and Body Mass Index (BMI) in the Japanese population.
Methods: We used administrative claims data from an advanced treatment hospital in Japan and extracted data from patients hospitalized for COVID-19. The exposure variable was BMI measured at the time of admission, and the study outcomes were progression to critical illness and death. Analyses were performed for each age group.
Results: Overall, 58,944 patients met the inclusion criteria. The risk of critical illness increased monotonically with higher BMI. In contrast, the relationship between BMI and mortality follows a J-shaped curve; being underweight and obese are risk factors for mortality. When stratified by age, similar trends were observed for both critical illness and mortality.
Conclusion: A higher BMI is a risk factor for the progression of COVID-19 severity, whereas both lower and higher BMIs are risk factors for mortality in the Japanese population.
Keywords: administrative claims database; body mass index; coronavirus disease 2019; obesity.