tetano
Editor, Senior Moderator
J Infect. 2020 Feb 26. pii: S0163-4453(20)30101-8. doi: 10.1016/j.jinf.2020.02.018. [Epub ahead of print] [h=1]Characteristics of COVID-19 infection in Beijing.[/h]
Tian S[SUP]1[/SUP], Hu N[SUP]2[/SUP], Lou J[SUP]1[/SUP], Chen K[SUP]3[/SUP], Kang X[SUP]1[/SUP], Xiang Z[SUP]2[/SUP], Chen H[SUP]2[/SUP], Wang D[SUP]4[/SUP], Liu N[SUP]5[/SUP], Liu D[SUP]6[/SUP], Chen G[SUP]7[/SUP], Zhang Y[SUP]8[/SUP], Li D[SUP]2[/SUP], Li J[SUP]2[/SUP], Lian H[SUP]1[/SUP], Niu S[SUP]1[/SUP], Zhang L[SUP]1[/SUP], Zhang J[SUP]9[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] [h=4]BACKGROUND:[/h] Since the first case of a novel coronavirus (COVID-19) infection pneumonia was detected in Wuhan, China, a series of confirmed cases of the COVID-19 were found in Beijing. We analyzed the data of 262 confirmed cases to determine the clinical and epidemiological characteristics of COVID-19 in Beijing.
[h=4]METHODS:[/h] We collected patients who were transferred by Beijing Emergency Medical Sevice to the designated hospitals. The information on demographic, epidemiological, clinical, laboratory test for the COVID-19 virus, diagnostic classification, cluster case and outcome were obtained. Furthermore we compared the characteristics between severe and common confirmed cases which including mild cases, no-pneumonia cases and asymptomatic cases, and we also compared the features between COVID-19 and 2003 SARS.
[h=4]FINDINGS:[/h] By Feb 10, 2020, 262 patients were transferred from the hospitals across Beijing to the designated hospitals for special treatment of the COVID-19 infected by Beijing emergency medical service. Among of 262 patients, 46 (17.6%) were severe cases, 216 (82.4%) were common cases, which including 192 (73.3%) mild cases, 11(4.2%) non-pneumonia cases and 13 (5.0%) asymptomatic cases respectively. The median age of patients was 47.5 years old and 48.5% were male. 192 (73.3%) patients were residents of Beijing, 50 (26.0%) of which had been to Wuhan, 116 (60.4%) had close contact with confirmed cases, 21 (10.9%) had no contact history. The most common symptoms at the onset of illness were fever (82.1%), cough (45.8%), fatigue (26.3%), dyspnea (6.9%) and headache (6.5%). The median incubation period was 6.7 days, the interval time from between illness onset and seeing a doctor was 4.5 days. As of Feb 10, 17.2% patients have discharged and 81.7% patients remain in hospital in our study, the fatality of COVID-19 infection in Beijing was 0.9%.
[h=4]INTERPRETATION:[/h] On the basis of this study, we provided the ratio of the COVID-19 infection on the severe cases to the mild, asymptomatic and non-pneumonia cases in Beijing. Population was generally susceptible, and with a relatively low fatality rate. The measures to prevent transmission was very successful at early stage, the next steps on the COVID-19 infection should be focused on early isolation of patients and quarantine for close contacts in families and communities in Beijing.
[h=4]FUNDING:[/h] Beijing Municipal Science and Technology Commission and Ministry of Science and Technology.
Copyright ? 2020 Elsevier Ltd. All rights reserved.
[h=4]KEYWORDS:[/h] 2019-nCoV; Beijing; COVID-19; Characteristics
PMID: 32112886 DOI: 10.1016/j.jinf.2020.02.018
Tian S[SUP]1[/SUP], Hu N[SUP]2[/SUP], Lou J[SUP]1[/SUP], Chen K[SUP]3[/SUP], Kang X[SUP]1[/SUP], Xiang Z[SUP]2[/SUP], Chen H[SUP]2[/SUP], Wang D[SUP]4[/SUP], Liu N[SUP]5[/SUP], Liu D[SUP]6[/SUP], Chen G[SUP]7[/SUP], Zhang Y[SUP]8[/SUP], Li D[SUP]2[/SUP], Li J[SUP]2[/SUP], Lian H[SUP]1[/SUP], Niu S[SUP]1[/SUP], Zhang L[SUP]1[/SUP], Zhang J[SUP]9[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] [h=4]BACKGROUND:[/h] Since the first case of a novel coronavirus (COVID-19) infection pneumonia was detected in Wuhan, China, a series of confirmed cases of the COVID-19 were found in Beijing. We analyzed the data of 262 confirmed cases to determine the clinical and epidemiological characteristics of COVID-19 in Beijing.
[h=4]METHODS:[/h] We collected patients who were transferred by Beijing Emergency Medical Sevice to the designated hospitals. The information on demographic, epidemiological, clinical, laboratory test for the COVID-19 virus, diagnostic classification, cluster case and outcome were obtained. Furthermore we compared the characteristics between severe and common confirmed cases which including mild cases, no-pneumonia cases and asymptomatic cases, and we also compared the features between COVID-19 and 2003 SARS.
[h=4]FINDINGS:[/h] By Feb 10, 2020, 262 patients were transferred from the hospitals across Beijing to the designated hospitals for special treatment of the COVID-19 infected by Beijing emergency medical service. Among of 262 patients, 46 (17.6%) were severe cases, 216 (82.4%) were common cases, which including 192 (73.3%) mild cases, 11(4.2%) non-pneumonia cases and 13 (5.0%) asymptomatic cases respectively. The median age of patients was 47.5 years old and 48.5% were male. 192 (73.3%) patients were residents of Beijing, 50 (26.0%) of which had been to Wuhan, 116 (60.4%) had close contact with confirmed cases, 21 (10.9%) had no contact history. The most common symptoms at the onset of illness were fever (82.1%), cough (45.8%), fatigue (26.3%), dyspnea (6.9%) and headache (6.5%). The median incubation period was 6.7 days, the interval time from between illness onset and seeing a doctor was 4.5 days. As of Feb 10, 17.2% patients have discharged and 81.7% patients remain in hospital in our study, the fatality of COVID-19 infection in Beijing was 0.9%.
[h=4]INTERPRETATION:[/h] On the basis of this study, we provided the ratio of the COVID-19 infection on the severe cases to the mild, asymptomatic and non-pneumonia cases in Beijing. Population was generally susceptible, and with a relatively low fatality rate. The measures to prevent transmission was very successful at early stage, the next steps on the COVID-19 infection should be focused on early isolation of patients and quarantine for close contacts in families and communities in Beijing.
[h=4]FUNDING:[/h] Beijing Municipal Science and Technology Commission and Ministry of Science and Technology.
Copyright ? 2020 Elsevier Ltd. All rights reserved.
[h=4]KEYWORDS:[/h] 2019-nCoV; Beijing; COVID-19; Characteristics
PMID: 32112886 DOI: 10.1016/j.jinf.2020.02.018