tetano
Editor, Senior Moderator
J Hosp Med
. 2021 Feb 5.
doi: 10.12788/jhm.3599. Online ahead of print.
Trends in Risk-Adjusted 28-Day Mortality Rates for Patients Hospitalized with COVID-19 in England
Simon Jones[SUP] 1 2 3 [/SUP], Neil Mason[SUP] 1 [/SUP], Tom Palser[SUP] 1 4 5 [/SUP], Simon Swift[SUP] 1 6 [/SUP], Christopher M Petrilli[SUP] 7 [/SUP], Leora I Horwitz[SUP] 2 3 [/SUP]
Affiliations
Abstract
Early reports showed high mortality from coronavirus disease 2019 (COVID-19). Mortality rates have recently been lower; however, patients are also now younger, with fewer comorbidities. We explored 28-day mortality for patients hospitalized for COVID-19 in England over a 5-month period, adjusting for a range of potentially mitigating variables, including sociodemographics and comorbidities. Among 102,610 hospitalizations, crude mortality decreased from 33.4% (95% CI, 32.9-34.0) in March 2020 to 15.5% (95% CI, 14.1-17.0) in July. Adjusted mortality decreased from 33.4% (95% CI, 32.8-34.1) in March to 17.4% (95% CI, 11.3-26.9) in July. The relative risk of mortality decreased from a reference of 1 in March to 0.52 (95% CI, 0.34-0.80) in July. This demonstrates that the reduction in mortality is not solely due to changes in the demographics of those with COVID-19.
. 2021 Feb 5.
doi: 10.12788/jhm.3599. Online ahead of print.
Trends in Risk-Adjusted 28-Day Mortality Rates for Patients Hospitalized with COVID-19 in England
Simon Jones[SUP] 1 2 3 [/SUP], Neil Mason[SUP] 1 [/SUP], Tom Palser[SUP] 1 4 5 [/SUP], Simon Swift[SUP] 1 6 [/SUP], Christopher M Petrilli[SUP] 7 [/SUP], Leora I Horwitz[SUP] 2 3 [/SUP]
Affiliations
- PMID: 33617437
- DOI: 10.12788/jhm.3599
Abstract
Early reports showed high mortality from coronavirus disease 2019 (COVID-19). Mortality rates have recently been lower; however, patients are also now younger, with fewer comorbidities. We explored 28-day mortality for patients hospitalized for COVID-19 in England over a 5-month period, adjusting for a range of potentially mitigating variables, including sociodemographics and comorbidities. Among 102,610 hospitalizations, crude mortality decreased from 33.4% (95% CI, 32.9-34.0) in March 2020 to 15.5% (95% CI, 14.1-17.0) in July. Adjusted mortality decreased from 33.4% (95% CI, 32.8-34.1) in March to 17.4% (95% CI, 11.3-26.9) in July. The relative risk of mortality decreased from a reference of 1 in March to 0.52 (95% CI, 0.34-0.80) in July. This demonstrates that the reduction in mortality is not solely due to changes in the demographics of those with COVID-19.