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J Eur Acad Dermatol Venereol . Skin manifestations of the BNT162b2 mRNA COVID-19 vaccine in healthcare workers. "COVID-arm": a clinical and histolo

tetano

Editor, Senior Moderator
J Eur Acad Dermatol Venereol


. 2021 Mar 30.
doi: 10.1111/jdv.17250. Online ahead of print.
Skin manifestations of the BNT162b2 mRNA COVID-19 vaccine in healthcare workers. "COVID-arm": a clinical and histological characterization


D Fernandez-Nieto[SUP] 1 [/SUP], J Hammerle[SUP] 2 [/SUP], M Fernandez-Escribano[SUP] 2 [/SUP], C M Moreno-Del Real[SUP] 3 [/SUP], P Garcia-Abellas[SUP] 3 [/SUP], I Carretero-Barrio[SUP] 3 [/SUP], E Solano-Solares[SUP] 4 [/SUP], B de-la-Hoz-Caballer[SUP] 4 [/SUP], J Jimenez-Cauhe[SUP] 1 [/SUP], D Ortega-Quijano[SUP] 1 [/SUP], M Fernandez-Guarino[SUP] 1 [/SUP]



Affiliations

Abstract

The coronavirus disease 2019 (COVID-19) has been associated to a wide clinical spectrum of skin manifestations, including chilblain-like, urticarial, vesicular, maculopapular, livedoid and vasculitic lesions, among others[SUP]1,2[/SUP] . However, the exact pathophysiology for the appearance of skin lesions is still unknown. Several hypotheses have been suggested, including viral hypersensitivity reactions, overexpression of type I interferons, COVID-19 induced coagulopathy, thrombotic microangiopathy and direct viral damage[SUP]3-6[/SUP] .

Keywords: SARS; coronavirus; delayed hypersensitivity; exanthem; vaccination.
 
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