tetano
Editor, Senior Moderator
J Endocr Soc
. 2022 Feb 16;6(4):bvac024.
doi: 10.1210/jendso/bvac024. eCollection 2022 Apr 1.
Pediatric Diabetes on the Rise: Trends in Incident Diabetes During the COVID-19 Pandemic
Rachel Modarelli[SUP] 1 [/SUP], Salma Sarah[SUP] 2 [/SUP], Megan E Ramaker[SUP] 3 [/SUP], Mboli Bolobiongo[SUP] 4 [/SUP], Robert Benjamin[SUP] 2 [/SUP], Pinar Gumus Balikcioglu[SUP] 2 3 [/SUP]
Affiliations
Abstract
Context: The effects of the coronavirus disease 2019 (COVID-19) pandemic on the incident cases of pediatric type 1 diabetes (T1D) and type 2 diabetes (T2D) are not clear.
Objective: To identify trends in incidence and presentation of pediatric new-onset T1D and T2D during the COVID-19 pandemic.
Methods: A retrospective chart review was conducted. Demographics, anthropometrics, and initial laboratory results from patients ages 0 through 21 years who presented with new-onset diabetes to a pediatric tertiary care center were recorded.
Results: During the pandemic, incident cases of pediatric T1D increased from 31 in each of the prior 2 years to 46; an increase of 48%. Incident cases of pediatric T2D increased by 231% from 2019 to 2020. The number of incident cases of pediatric T2D increased significantly more than the number of incident cases of pediatric T1D (P = 0.009). Patients with T2D were more likely to present in diabetic ketoacidosis (DKA), though this was not statistically significant (P = 0.093). Severe DKA was higher compared with moderate DKA (P = 0.036) in incident cases of pediatric T2D. During the pandemic, for the first time, incident cases of T2D accounted for more than one-half of all newly diagnosed pediatric diabetes cases (53%).
Conclusions: There were more incident pediatric T1D and T2D cases as well as an increase in DKA severity in T2D at presentation during the COVID-19 pandemic. More importantly, incident T2D cases were higher than the incident T1D during the pandemic. This clearly suggests a disruption and change in the pediatric diabetes trends with profound individual and community health consequences.
Keywords: COVID-19; diabetic ketoacidosis; pediatric diabetes; type 1 diabetes; type 2 diabetes.
. 2022 Feb 16;6(4):bvac024.
doi: 10.1210/jendso/bvac024. eCollection 2022 Apr 1.
Pediatric Diabetes on the Rise: Trends in Incident Diabetes During the COVID-19 Pandemic
Rachel Modarelli[SUP] 1 [/SUP], Salma Sarah[SUP] 2 [/SUP], Megan E Ramaker[SUP] 3 [/SUP], Mboli Bolobiongo[SUP] 4 [/SUP], Robert Benjamin[SUP] 2 [/SUP], Pinar Gumus Balikcioglu[SUP] 2 3 [/SUP]
Affiliations
- PMID: 35265783
- PMCID: PMC8900286
- DOI: 10.1210/jendso/bvac024
Abstract
Context: The effects of the coronavirus disease 2019 (COVID-19) pandemic on the incident cases of pediatric type 1 diabetes (T1D) and type 2 diabetes (T2D) are not clear.
Objective: To identify trends in incidence and presentation of pediatric new-onset T1D and T2D during the COVID-19 pandemic.
Methods: A retrospective chart review was conducted. Demographics, anthropometrics, and initial laboratory results from patients ages 0 through 21 years who presented with new-onset diabetes to a pediatric tertiary care center were recorded.
Results: During the pandemic, incident cases of pediatric T1D increased from 31 in each of the prior 2 years to 46; an increase of 48%. Incident cases of pediatric T2D increased by 231% from 2019 to 2020. The number of incident cases of pediatric T2D increased significantly more than the number of incident cases of pediatric T1D (P = 0.009). Patients with T2D were more likely to present in diabetic ketoacidosis (DKA), though this was not statistically significant (P = 0.093). Severe DKA was higher compared with moderate DKA (P = 0.036) in incident cases of pediatric T2D. During the pandemic, for the first time, incident cases of T2D accounted for more than one-half of all newly diagnosed pediatric diabetes cases (53%).
Conclusions: There were more incident pediatric T1D and T2D cases as well as an increase in DKA severity in T2D at presentation during the COVID-19 pandemic. More importantly, incident T2D cases were higher than the incident T1D during the pandemic. This clearly suggests a disruption and change in the pediatric diabetes trends with profound individual and community health consequences.
Keywords: COVID-19; diabetic ketoacidosis; pediatric diabetes; type 1 diabetes; type 2 diabetes.