tetano
Editor, Senior Moderator
J Community Health Nurs
. 2025 Jan 16:1-15.
doi: 10.1080/07370016.2025.2452164. Online ahead of print. Strategies for Influenza Outbreak Management in a US Residential Summer Camp Communal Housing: A Comparative Analysis of Targeted Antiviral Prophylaxis
Sandra D Shapiro[SUP] 1 [/SUP], Michelle DeDeo[SUP] 2 [/SUP], Amber Barnes[SUP] 3 [/SUP]
Affiliations
Background: Previous research has underscored the efficacy of individual control strategies in mitigating influenza spread within communal settings; however, the unique dynamics of residential summer camps-characterized by close contact and high social interaction-present distinct challenges for outbreak management.
Purpose: The purpose of this study was to evaluate and compare the effectiveness of two targeted antiviral prophylaxis protocols using oseltamivir in controlling influenza outbreaks within a residential youth camp, aiming to provide evidence-based insights for optimizing outbreak management in communal settings with high social interaction.
Design: This retrospective study analyzed the progression of influenza outbreaks in a residential youth camp using two antiviral prophylaxis protocols with oseltamivir. Time-series models assessed outbreak dynamics, and descriptive statistics characterized camp cohorts to evaluate the effectiveness of mass chemoprophylaxis (2022 Protocol) versus more rapidly deployed chemoprophylaxis (2023 Protocol).
Methods: We used descriptive statistics to define the camp cohorts and time-series models to analyze the outbreak's progression under each protocol.
Findings: In 2022, oseltamivir was widely distributed after the outbreak began, likely resulting in a reduced but ongoing spread. In 2023, targeted use of oseltamivir early in the outbreak significantly reduced transmission within the camp.
Conclusion: The study demonstrated oseltamivir's efficacy in reducing influenza transmission and emphasized the importance of rapid intervention in communal settings, offering valuable insights for optimizing outbreak management.
Clinical evidence: Early intervention with oseltamivir was more effective in controlling the outbreak than a later intervention. Targeted use of oseltamivir, focusing on individuals exposed to the virus, was shown to be beneficial.
. 2025 Jan 16:1-15.
doi: 10.1080/07370016.2025.2452164. Online ahead of print. Strategies for Influenza Outbreak Management in a US Residential Summer Camp Communal Housing: A Comparative Analysis of Targeted Antiviral Prophylaxis
Sandra D Shapiro[SUP] 1 [/SUP], Michelle DeDeo[SUP] 2 [/SUP], Amber Barnes[SUP] 3 [/SUP]
Affiliations
- PMID: 39817613
- DOI: 10.1080/07370016.2025.2452164
Background: Previous research has underscored the efficacy of individual control strategies in mitigating influenza spread within communal settings; however, the unique dynamics of residential summer camps-characterized by close contact and high social interaction-present distinct challenges for outbreak management.
Purpose: The purpose of this study was to evaluate and compare the effectiveness of two targeted antiviral prophylaxis protocols using oseltamivir in controlling influenza outbreaks within a residential youth camp, aiming to provide evidence-based insights for optimizing outbreak management in communal settings with high social interaction.
Design: This retrospective study analyzed the progression of influenza outbreaks in a residential youth camp using two antiviral prophylaxis protocols with oseltamivir. Time-series models assessed outbreak dynamics, and descriptive statistics characterized camp cohorts to evaluate the effectiveness of mass chemoprophylaxis (2022 Protocol) versus more rapidly deployed chemoprophylaxis (2023 Protocol).
Methods: We used descriptive statistics to define the camp cohorts and time-series models to analyze the outbreak's progression under each protocol.
Findings: In 2022, oseltamivir was widely distributed after the outbreak began, likely resulting in a reduced but ongoing spread. In 2023, targeted use of oseltamivir early in the outbreak significantly reduced transmission within the camp.
Conclusion: The study demonstrated oseltamivir's efficacy in reducing influenza transmission and emphasized the importance of rapid intervention in communal settings, offering valuable insights for optimizing outbreak management.
Clinical evidence: Early intervention with oseltamivir was more effective in controlling the outbreak than a later intervention. Targeted use of oseltamivir, focusing on individuals exposed to the virus, was shown to be beneficial.