tetano
Editor, Senior Moderator
J Clin Med
. 2022 Dec 13;11(24):7386.
doi: 10.3390/jcm11247386.
The Clinical Course and Outcomes of Patients Hospitalized Due to COVID-19 during Three Pandemic Waves in Poland: A Single Center Observational Study
Carlo Bieńkowski[SUP] 1 2 [/SUP], Justyna D Kowalska[SUP] 1 2 [/SUP], Marcin Paciorek[SUP] 1 2 [/SUP], Piotr Wasilewski[SUP] 1 3 [/SUP], Paweł Uliczny[SUP] 1 [/SUP], Ewelina Garbacz-Łagożna[SUP] 1 [/SUP], Andrzej Pihowicz[SUP] 1 [/SUP], Monika Mrozińska[SUP] 1 [/SUP], Tomasz Dyda[SUP] 1 [/SUP], Michał Makowiecki[SUP] 1 2 [/SUP], Joanna Puła[SUP] 1 2 [/SUP], Andrzej Horban[SUP] 1 2 [/SUP]
Affiliations
Abstract
Background: The first case of coronavirus disease 2019 (COVID-19) in Poland was reported on 4 March 2020. We aim to compare the clinical course and outcomes of patients hospitalized in the Hospital for Infectious Diseases in Warsaw due to COVID-19 during three pandemic waves.
Materials and methods: The medical data were collected for all patients diagnosed with COVID-19 hospitalized in our hospital from 6 March 2020 till 30 November 2021. COVID-19 diagnosis was confirmed by nasopharyngeal swabs using real-time polymerase chain reaction assay (RT-PCR) or SARS-CoV-2 antigen test. COVID-19 waves were defined based on the number and dynamics of cases.
Results: Altogether, 2138 patient medical records were analyzed. The majority of the cohort was male (1235/2138, 57.8%), and the median age was 65 years [IQR: 50-74 years]. Patients hospitalized during the third wave had lower oxygen saturation on admission (p < 0.001) and were more likely to receive oxygen supplementation (p < 0.001). Serious complications, including pneumothorax (p < 0.001) and thromboembolic complications (p < 0.001), intensive care unit admission (p = 0.034), and death (p = 0.003), occurred more often in patients of the third wave.
Conclusions: During the third wave, patients in our cohort experienced a more severe course of the disease and poorer outcomes.
Keywords: COVID-19; SARS-CoV-2; epidemic waves; pandemic.
. 2022 Dec 13;11(24):7386.
doi: 10.3390/jcm11247386.
The Clinical Course and Outcomes of Patients Hospitalized Due to COVID-19 during Three Pandemic Waves in Poland: A Single Center Observational Study
Carlo Bieńkowski[SUP] 1 2 [/SUP], Justyna D Kowalska[SUP] 1 2 [/SUP], Marcin Paciorek[SUP] 1 2 [/SUP], Piotr Wasilewski[SUP] 1 3 [/SUP], Paweł Uliczny[SUP] 1 [/SUP], Ewelina Garbacz-Łagożna[SUP] 1 [/SUP], Andrzej Pihowicz[SUP] 1 [/SUP], Monika Mrozińska[SUP] 1 [/SUP], Tomasz Dyda[SUP] 1 [/SUP], Michał Makowiecki[SUP] 1 2 [/SUP], Joanna Puła[SUP] 1 2 [/SUP], Andrzej Horban[SUP] 1 2 [/SUP]
Affiliations
- PMID: 36556002
- DOI: 10.3390/jcm11247386
Abstract
Background: The first case of coronavirus disease 2019 (COVID-19) in Poland was reported on 4 March 2020. We aim to compare the clinical course and outcomes of patients hospitalized in the Hospital for Infectious Diseases in Warsaw due to COVID-19 during three pandemic waves.
Materials and methods: The medical data were collected for all patients diagnosed with COVID-19 hospitalized in our hospital from 6 March 2020 till 30 November 2021. COVID-19 diagnosis was confirmed by nasopharyngeal swabs using real-time polymerase chain reaction assay (RT-PCR) or SARS-CoV-2 antigen test. COVID-19 waves were defined based on the number and dynamics of cases.
Results: Altogether, 2138 patient medical records were analyzed. The majority of the cohort was male (1235/2138, 57.8%), and the median age was 65 years [IQR: 50-74 years]. Patients hospitalized during the third wave had lower oxygen saturation on admission (p < 0.001) and were more likely to receive oxygen supplementation (p < 0.001). Serious complications, including pneumothorax (p < 0.001) and thromboembolic complications (p < 0.001), intensive care unit admission (p = 0.034), and death (p = 0.003), occurred more often in patients of the third wave.
Conclusions: During the third wave, patients in our cohort experienced a more severe course of the disease and poorer outcomes.
Keywords: COVID-19; SARS-CoV-2; epidemic waves; pandemic.