tetano
Editor, Senior Moderator
J Clin Med Res
. 2020 May;12(5):315-319.
doi: 10.14740/jocmr4173. Epub 2020 May 8.
A Comprehensive Approach Is Vital for Diagnosing COVID-19: A Case of False Negative
Mamtha Balla[SUP] 1 2 [/SUP], Ganesh Prasad Merugu[SUP] 3 [/SUP], Mytri Pokal[SUP] 4 [/SUP], Vijay Gayam[SUP] 5 [/SUP], Sreedhar Adapa[SUP] 6 [/SUP], Srikanth Naramala[SUP] 7 [/SUP], Venu Madhav Konala[SUP] 8 [/SUP]
Affiliations
Abstract
Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is spreading at a rapid pace throughout the world, and the World Health Organization (WHO) declared it as pandemic on March 11, 2020. We present a case of COVID-19 patient whose reverse transcription-polymerase chain reaction (RT-PCR) initially was false negative and later turned positive, which will stress the importance of a comprehensive approach while evaluating a patient with a differential of COVID-19. The clinicians should be aware of the sensitivity and specificities of these tests which can have grave implications on the patient and community if the diagnosis is missed just based on the laboratory tests due to the highly contagious nature of the disease.
Keywords: COVID-19; Comprehensive approach; False negative; RT-PCR; Testing; True positives.
. 2020 May;12(5):315-319.
doi: 10.14740/jocmr4173. Epub 2020 May 8.
A Comprehensive Approach Is Vital for Diagnosing COVID-19: A Case of False Negative
Mamtha Balla[SUP] 1 2 [/SUP], Ganesh Prasad Merugu[SUP] 3 [/SUP], Mytri Pokal[SUP] 4 [/SUP], Vijay Gayam[SUP] 5 [/SUP], Sreedhar Adapa[SUP] 6 [/SUP], Srikanth Naramala[SUP] 7 [/SUP], Venu Madhav Konala[SUP] 8 [/SUP]
Affiliations
- PMID: 32489507
- PMCID: PMC7239581
- DOI: 10.14740/jocmr4173
Abstract
Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is spreading at a rapid pace throughout the world, and the World Health Organization (WHO) declared it as pandemic on March 11, 2020. We present a case of COVID-19 patient whose reverse transcription-polymerase chain reaction (RT-PCR) initially was false negative and later turned positive, which will stress the importance of a comprehensive approach while evaluating a patient with a differential of COVID-19. The clinicians should be aware of the sensitivity and specificities of these tests which can have grave implications on the patient and community if the diagnosis is missed just based on the laboratory tests due to the highly contagious nature of the disease.
Keywords: COVID-19; Comprehensive approach; False negative; RT-PCR; Testing; True positives.