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J Cardiol Cases . Constrictive pericarditis following mRNA COVID-19 vaccination in a patient with systemic sclerosis

tetano

Editor, Senior Moderator
J Cardiol Cases


. 2022 Apr 4.
doi: 10.1016/j.jccase.2022.03.014. Online ahead of print.
Constrictive pericarditis following mRNA COVID-19 vaccination in a patient with systemic sclerosis


Ikuo Misumi[SUP] 1 [/SUP], Aki Ogata[SUP] 2 [/SUP], Koichiro Fukuda[SUP] 3 [/SUP], Koji Sato[SUP] 1 [/SUP], Miwa Nagano[SUP] 1 [/SUP], Hiroki Usuku[SUP] 4 [/SUP], Kenichi Tsujita[SUP] 4 [/SUP]



Affiliations

Abstract

A 59-year-old man with systemic sclerosis and interstitial pneumonia was referred to our department because he developed dyspnea and leg edema after receiving a first shot of coronavirus disease 2019 (COVID-19) vaccine. Transthoracic echocardiography showed moderate pericardial effusion with conspicuous fibrin deposition. Prednisolone was increased from 6 mg/day for systemic sclerosis to 20 mg/day. Thereafter, pericardial effusion gradually decreased. However, his symptoms continued. Transthoracic echocardiography showed disappearance of pericardial effusion and thickened pericardium. Pulsed-wave and tissue Doppler echocardiography revealed that the patient suffered from newly developed constrictive pericarditis. COVID-19 vaccination might have contributed to acute pericarditis and subsequent constrictive pericarditis in the present case of systemic sclerosis and pulmonary fibrosis. Learning objective Incidence of adverse effects after coronavirus disease 2019 vaccination is rare. The present case suggests the risk of pericarditis that may lead to constrictive pericarditis.

Keywords: Constrictive pericarditis; Coronavirus disease 2019 vaccine; Steroid; Systemic sclerosis.
 
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