tetano
Editor, Senior Moderator
J Autoimmun. 2020 Feb 26:102433. doi: 10.1016/j.jaut.2020.102433. [Epub ahead of print] [h=1]The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak.[/h]
Rothan HA[SUP]1[/SUP], Byrareddy SN[SUP]2[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Coronavirus disease (COVID-19) is caused by SARS-COV2 and represents the causative agent of a potentially fatal disease that is of great global public health concern. Based on the large number of infected people that were exposed to the wet animal market in Wuhan City, China, it is suggested that this is likely the zoonotic origin of COVID-19. Person-to-person transmission of COVID-19 infection led to the isolation of patients that were subsequently administered a variety of treatments. Extensive measures to reduce person-to-person transmission of COVID-19 have been implemented to control the current outbreak. Special attention and efforts to protect or reduce transmission should be applied in susceptible populations including children, health care providers, and elderly people. In this review, we highlights the symptoms, epidemiology, transmission, pathogenesis, phylogenetic analysis and future directions to control the spread of this fatal disease.
Copyright ? 2020 Elsevier Ltd. All rights reserved.
[h=4]KEYWORDS:[/h] COVID-19; Coronavirus; Pathogenesis; Pneumonia; Wuhan city
PMID: 32113704 DOI: 10.1016/j.jaut.2020.102433
Rothan HA[SUP]1[/SUP], Byrareddy SN[SUP]2[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Coronavirus disease (COVID-19) is caused by SARS-COV2 and represents the causative agent of a potentially fatal disease that is of great global public health concern. Based on the large number of infected people that were exposed to the wet animal market in Wuhan City, China, it is suggested that this is likely the zoonotic origin of COVID-19. Person-to-person transmission of COVID-19 infection led to the isolation of patients that were subsequently administered a variety of treatments. Extensive measures to reduce person-to-person transmission of COVID-19 have been implemented to control the current outbreak. Special attention and efforts to protect or reduce transmission should be applied in susceptible populations including children, health care providers, and elderly people. In this review, we highlights the symptoms, epidemiology, transmission, pathogenesis, phylogenetic analysis and future directions to control the spread of this fatal disease.
Copyright ? 2020 Elsevier Ltd. All rights reserved.
[h=4]KEYWORDS:[/h] COVID-19; Coronavirus; Pathogenesis; Pneumonia; Wuhan city
PMID: 32113704 DOI: 10.1016/j.jaut.2020.102433