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J Asthma . The Impact of Asthma on COVID-19 Disease Severity in Children and Adolescents

tetano

Editor, Senior Moderator
J Asthma


. 2022 Oct 6;1-18.
doi: 10.1080/02770903.2022.2132956. Online ahead of print.
The Impact of Asthma on COVID-19 Disease Severity in Children and Adolescents


Emily Robbins[SUP] 1 [/SUP], Seleshi Demissie[SUP] 2 3 [/SUP], Steven Daoud[SUP] 1 [/SUP], Pushpom James[SUP] 1 3 [/SUP]



Affiliations

Abstract

Background: Atopy and allergic asthma have been found to be protective against coronavirus disease (COVID-19) in adults but have not been studied in children.Objective: To identify whether children and adolescents with asthma had less severe disease and lower morbidity from COVID-19 than their counterparts without asthma.Methods: This was a retrospective chart review from March 1, 2020, through January 31, 2021. Charts were eligible for inclusion if patients were over 6 years of age and below 20 years of age and tested positive for COVID-19 by PCR or antigen testing or were COVID-19 antibody positive when they presented to the emergency department (ED). Patients were grouped according to disease severity and divided into two groups, those with asthma and those without. A total of 1,585 patients were included-1,492 without asthma and 93 with asthma.Results: Children and adolescents with asthma are less likely to be seen in the ED for COVID-19-related disease (p value< 0.0001, but if they presented to the ED, they were significantly more likely to be hospitalized, require oxygen, and have more severe forms of COVID-19 than children and adolescents without asthma (p value< 0.0001).Conclusions: Children and adolescents with asthma, though less likely to be seen in ED with COVID-19, were more likely to have severe disease than patients without asthma, once they presented to the ED.

Keywords: asthma; comorbidities; coronavirus disease 2019 (COVID-19); pediatrics.
 
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