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J Arrhythm . New-onset atrial fibrillation in critically ill patients with coronavirus disease 2019 (COVID-19)

tetano

Editor, Senior Moderator
J Arrhythm


. 2021 Aug 16;10.1002/joa3.12619.
doi: 10.1002/joa3.12619. Online ahead of print.
New-onset atrial fibrillation in critically ill patients with coronavirus disease 2019 (COVID-19)


Bişar Ergün[SUP] 1 [/SUP], Begüm Ergan[SUP] 2 [/SUP], Melih Kaan Sözmen[SUP] 3 [/SUP], Murat Küçük[SUP] 1 [/SUP], Mehmet Nuri Yakar[SUP] 4 [/SUP], Bilgin Cömert[SUP] 1 [/SUP], Ali Necati Gökmen[SUP] 4 [/SUP], Erdem Yaka[SUP] 5 [/SUP]



Affiliations

Abstract

Background: Mortality in critically ill patients with coronavirus disease 2019 (COVID-19) is high, therefore, it is essential to evaluate the independent effect of new-onset atrial fibrillation (NOAF) on mortality in patients with COVID-19. We aimed to determine the incidence, risk factors, and outcomes of NOAF in a cohort of critically ill patients with COVID-19.
Methods: We conducted a retrospective study on patients admitted to the intensive care unit (ICU) with a diagnosis of COVID-19. NOAF was defined as atrial fibrillation that was detected after diagnosis of COVID-19 without a prior history. The primary outcome of the study was the effect of NOAF on mortality in critically ill COVID-19 patients.
Results: NOAF incidence was 14.9% (n = 37), and 78% of patients (n = 29) were men in NOAF positive group. Median age of the NOAF group was 79.0 (interquartile range, 71.5-84.0). Hospital mortality was higher in the NOAF group (87% vs 67%, respectively, P = .019). However, in multivariate analysis, NOAF was not an independent risk factor for hospital mortality (OR 1.42, 95% CI 0.40-5.09, P = .582).
Conclusions: The incidence of NOAF was 14.9% in critically ill COVID-19 patients. Hospital mortality was higher in the NOAF group. However, NOAF was not an independent risk factor for hospital mortality in patients with COVID-19.

Keywords: COVID‐19; atrial fibrillation; critical care; hospital mortality; intensive care unit.
 
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