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J Anesth . Clinical characteristics and outcomes of critically ill patients with COVID-19 in Kobe, Japan: a single-center, retrospective, observatio

tetano

Editor, Senior Moderator
J Anesth


. 2021 Jan 23.
doi: 10.1007/s00540-021-02897-w. Online ahead of print.
Clinical characteristics and outcomes of critically ill patients with COVID-19 in Kobe, Japan: a single-center, retrospective, observational study


Jiro Ito[SUP] 1 [/SUP], Ryutaro Seo[SUP] 2 [/SUP], Daisuke Kawakami[SUP] 3 [/SUP], Yoshinori Matsuoka[SUP] 2 [/SUP], Kenjiro Ouchi[SUP] 3 [/SUP], Suguru Nonami[SUP] 3 [/SUP], Yusuke Miyoshi[SUP] 3 [/SUP], Masao Tatebe[SUP] 3 [/SUP], Takahiro Tsuchida[SUP] 3 [/SUP], Yoko Asaka[SUP] 2 [/SUP], Machi Yanai[SUP] 2 [/SUP], Hiroshi Ueta[SUP] 3 [/SUP], Takahiro Shimozono[SUP] 3 [/SUP], Hiroyuki Mima[SUP] 3 [/SUP], Asako Doi[SUP] 4 [/SUP], Keisuke Tomii[SUP] 5 [/SUP], Koichi Ariyoshi[SUP] 2 [/SUP]



Affiliations

Abstract

Purpose: Coronavirus disease 2019 (COVID-19) has placed a great burden on critical care services worldwide. Data regarding critically ill COVID-19 patients and their demand of critical care services outside of initial COVID-19 epicenters are lacking. This study described clinical characteristics and outcomes of critically ill COVID-19 patients and the capacity of a COVID-19-dedicated intensive care unit (ICU) in Kobe, Japan.
Methods: This retrospective observational study included critically ill COVID-19 patients admitted to a 14-bed COVID-19-dedicated ICU in Kobe between March 3, 2020 and June 21, 2020. Clinical and daily ICU occupancy data were obtained from electrical medical records. The last follow-up day was June 28, 2020.
Results: Of 32 patients included, the median hospital follow-up period was 27 (interquartile range 19-50) days. The median age was 68 (57-76) years; 23 (72%) were men and 25 (78%) had at least one comorbidity. Nineteen (59%) patients received invasive mechanical ventilation for a median duration of 14 (8-27) days. Until all patients were discharged from the ICU on June 5, 2020, the median daily ICU occupancy was 50% (36-71%). As of June 28, 2020, six (19%) died during hospitalization. Of 26 (81%) survivors, 23 (72%) were discharged from the hospital and three (9%) remained in the hospital.
Conclusion: During the first months of the outbreak in Kobe, most critically ill patients were men aged ≥ 60 years with at least one comorbidity and on mechanical ventilation; the ICU capacity was not strained, and the case-fatality rate was 19%.

Keywords: Bed occupancy; Coronavirus; Critical care; Mortality; Respiration, artificial; Respiratory distress syndrome, adult; Severe acute respiratory syndrome coronavirus 2.
 
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