tetano
Editor, Senior Moderator
J Am Coll Radiol. 2020 Mar 25. pii: S1546-1440(20)30262-3. doi: 10.1016/j.jacr.2020.03.006. [Epub ahead of print]
Coronavirus Disease 2019 (COVID-19) CT Findings: A Systematic Review and Meta-analysis.
Bao C[SUP]1[/SUP], Liu X[SUP]1[/SUP], Zhang H[SUP]1[/SUP], Li Y[SUP]2[/SUP], Liu J[SUP]3[/SUP].
Author information
Abstract
PURPOSE:
To date, considerable knowledge gaps remain regarding the chest CT imaging features of COVID-19. We performed a systematic review and meta-analysis of results from published studies to date to provide a summary of evidence on detection of COVID-19 by chest CT and the expected CT imaging manifestations.
METHODS:
Studies were identified by searching PubMed database for articles published between December 2019 and February 2020. Pooled CT positive rate of COVID-19 and pooled incidence of CT imaging findings were estimated using a random-effect model.
RESULTS:
A total of 13 studies met inclusion criteria. The pooled positive rate of the CT imaging was 89.76% and 90.35% when only including thin-section chest CT. Typical CT signs were ground glass opacities (83.31%), ground glass opacities with mixed consolidation (58.42%), adjacent pleura thickening (52.46%), interlobular septal thickening (48.46%), and air bronchograms (46.46%). Other CT signs included crazy paving pattern (14.81%), pleural effusion (5.88%), bronchiectasis (5.42%), pericardial effusion (4.55%), and lymphadenopathy (3.38%). The most anatomic distributions were bilateral lung infection (78.2%) and peripheral distribution (76.95%). The incidences were highest in the right lower lobe (87.21%), left lower lobe (81.41%), and bilateral lower lobes (65.22%). The right upper lobe (65.22%), right middle lobe (54.95%), and left upper lobe (69.43%) were also commonly involved. The incidence of bilateral upper lobes was 60.87%. A considerable proportion of patients had three or more lobes involved (70.81%).
CONCLUSIONS:
The detection of COVID-19 chest CT imaging is very high among symptomatic individuals at high risk, especially using thin-section chest CT. The most common CT features in patients affected by COVID-19 included ground glass opacities and consolidation involving the bilateral lungs in a peripheral distribution.
Copyright ? 2020 American College of Radiology. Published by Elsevier Inc. All rights reserved.
KEYWORDS:
COVID-19; CT imaging findings; ground glass opacities; meta-analysis; thin-section chest CT
PMID:32283052DOI:10.1016/j.jacr.2020.03.006
Coronavirus Disease 2019 (COVID-19) CT Findings: A Systematic Review and Meta-analysis.
Bao C[SUP]1[/SUP], Liu X[SUP]1[/SUP], Zhang H[SUP]1[/SUP], Li Y[SUP]2[/SUP], Liu J[SUP]3[/SUP].
Author information
Abstract
PURPOSE:
To date, considerable knowledge gaps remain regarding the chest CT imaging features of COVID-19. We performed a systematic review and meta-analysis of results from published studies to date to provide a summary of evidence on detection of COVID-19 by chest CT and the expected CT imaging manifestations.
METHODS:
Studies were identified by searching PubMed database for articles published between December 2019 and February 2020. Pooled CT positive rate of COVID-19 and pooled incidence of CT imaging findings were estimated using a random-effect model.
RESULTS:
A total of 13 studies met inclusion criteria. The pooled positive rate of the CT imaging was 89.76% and 90.35% when only including thin-section chest CT. Typical CT signs were ground glass opacities (83.31%), ground glass opacities with mixed consolidation (58.42%), adjacent pleura thickening (52.46%), interlobular septal thickening (48.46%), and air bronchograms (46.46%). Other CT signs included crazy paving pattern (14.81%), pleural effusion (5.88%), bronchiectasis (5.42%), pericardial effusion (4.55%), and lymphadenopathy (3.38%). The most anatomic distributions were bilateral lung infection (78.2%) and peripheral distribution (76.95%). The incidences were highest in the right lower lobe (87.21%), left lower lobe (81.41%), and bilateral lower lobes (65.22%). The right upper lobe (65.22%), right middle lobe (54.95%), and left upper lobe (69.43%) were also commonly involved. The incidence of bilateral upper lobes was 60.87%. A considerable proportion of patients had three or more lobes involved (70.81%).
CONCLUSIONS:
The detection of COVID-19 chest CT imaging is very high among symptomatic individuals at high risk, especially using thin-section chest CT. The most common CT features in patients affected by COVID-19 included ground glass opacities and consolidation involving the bilateral lungs in a peripheral distribution.
Copyright ? 2020 American College of Radiology. Published by Elsevier Inc. All rights reserved.
KEYWORDS:
COVID-19; CT imaging findings; ground glass opacities; meta-analysis; thin-section chest CT
PMID:32283052DOI:10.1016/j.jacr.2020.03.006