tetano
Editor, Senior Moderator
Ital J Pediatr
. 2022 Jul 27;48(1):130.
doi: 10.1186/s13052-022-01311-9.
MIS-C and co-infection with P. vivax and P. falciparum in a child: a clinical conundrum
Michela Scalisi[SUP] 1 [/SUP], Salvatore Giordano[SUP] 1 [/SUP], Laura Antonella Canduscio[SUP] 1 [/SUP], Maria Concetta Failla[SUP] 1 [/SUP], Luca Messina[SUP] 1 [/SUP], Elisa Sferrazza[SUP] 1 [/SUP], Raffaella Rubino[SUP] 2 [/SUP], Lucia Siracusa[SUP] 1 [/SUP], Veronica Vanella[SUP] 1 [/SUP], Antonio Cascio[SUP] 2 [/SUP], Claudia Colomba[SUP] 3 4 [/SUP]
Affiliations
Abstract
Background: The ongoing Coronavirus Disease 2019 (COVID-19) epidemic represents an unprecedented global health challenge. Many COVID-19 symptoms are similar to symptoms that can occur in other infections. Malaria should always be considered in patients with SARS-CoV-2 infection returning from endemic areas.
Case presentation: We present the first case of multisystem inflammatory syndrome (MIS-C) and Plasmodium vivax-falciparum and SARS-CoV2 coinfection in children. Despite clearance of parassitaemia and a negative COVID-19 nasopharyngeal PCR, the patient's clinical conditions worsened. The World Health Organization (WHO) criteria were used to make the diagnosis of MIS-C. Treatment with intravenous immunoglobulins and methylprednisolone was effective.
Conclusions: This case emphasizes the importance of considering malaria diagnosis in patients returning from endemic areas, even in the COVID 19 era. Malaria and SARS-CoV2 co-infection may increase the risk of MIS-C, for which early detection is critical for proper management.
Keywords: COVID-19; Case report; Malaria; Multisystem inflammatory syndrome; SARS CoV2.
. 2022 Jul 27;48(1):130.
doi: 10.1186/s13052-022-01311-9.
MIS-C and co-infection with P. vivax and P. falciparum in a child: a clinical conundrum
Michela Scalisi[SUP] 1 [/SUP], Salvatore Giordano[SUP] 1 [/SUP], Laura Antonella Canduscio[SUP] 1 [/SUP], Maria Concetta Failla[SUP] 1 [/SUP], Luca Messina[SUP] 1 [/SUP], Elisa Sferrazza[SUP] 1 [/SUP], Raffaella Rubino[SUP] 2 [/SUP], Lucia Siracusa[SUP] 1 [/SUP], Veronica Vanella[SUP] 1 [/SUP], Antonio Cascio[SUP] 2 [/SUP], Claudia Colomba[SUP] 3 4 [/SUP]
Affiliations
- PMID: 35897103
- DOI: 10.1186/s13052-022-01311-9
Abstract
Background: The ongoing Coronavirus Disease 2019 (COVID-19) epidemic represents an unprecedented global health challenge. Many COVID-19 symptoms are similar to symptoms that can occur in other infections. Malaria should always be considered in patients with SARS-CoV-2 infection returning from endemic areas.
Case presentation: We present the first case of multisystem inflammatory syndrome (MIS-C) and Plasmodium vivax-falciparum and SARS-CoV2 coinfection in children. Despite clearance of parassitaemia and a negative COVID-19 nasopharyngeal PCR, the patient's clinical conditions worsened. The World Health Organization (WHO) criteria were used to make the diagnosis of MIS-C. Treatment with intravenous immunoglobulins and methylprednisolone was effective.
Conclusions: This case emphasizes the importance of considering malaria diagnosis in patients returning from endemic areas, even in the COVID 19 era. Malaria and SARS-CoV2 co-infection may increase the risk of MIS-C, for which early detection is critical for proper management.
Keywords: COVID-19; Case report; Malaria; Multisystem inflammatory syndrome; SARS CoV2.